Student Projects
Jessica Andrews
Investigation of Lingo-1 pathways in the pathology and therapy of schizophrenia
Primary Supervisor Dr Francesca Fernandez-Enright
Bruce Ashford
Understanding the molecular and genetic mechanisms of metastasis in cutaneous squamous cell carcinoma
Primary Supervisor Professor Marie Ranson
Ilijana Babic
Improving schizophrenia treatment: a focus on cognition and the metabolic side-effects of medications
Primary Supervisor Dr Katrina Green
Rachelle Balez
Alterations in membranes and signalling pathways in Alzheimer's disease
Primary Supervisor Dr Lezanne Ooi
Rachael Bartlett
Exploring the roles of purinergic signalling in motor neurone disease
Primary Supervisor Associate Professor Ronald Sluyter
Monique Bax
Developing an induced pluripotent stem cell model to study protein degradation in motor neurone disease / amyotrophic lateral sclerosis
Primary Supervisor Dr Lezanne Ooi
Lisa Belfiore
Development of dual-targeted drug-loaded liposomes to target heterogeneous tumour cell populations in metastatic breast cancer
Primary Supervisor Dr Kara Perrow
Christopher Bell
The mechanism of antipsychotic drug action
Primary Supervisor Professor Xu-Feng Huang
Ronald Brown
Medicinal chemistry of neglected tropical diseases and copper catalysed aziridine ring-opening reactions
Primary Supervisor Dr Christopher Hyland
Rebecca Brown
The role of proteostasis in motor neurone disease
Primary Supervisor Senior Professor Mark Wilson
Daniel Brungs
Development of patient-derived gastric cancer cell models for genetic, phenotypic and drug response analysis
Primary Supervisor Professor Marie Ranson
Benjamin Buckley
Dual inhibition of anticancer targets uPA and NHE1
Primary Supervisor Professor Marie Ranson
Danielle Camer
The leptin sensitising effects of pentacyclic triterpenes in natural and esterified configurations in diet-induced obesity and potential cognitive benefits
Primary Supervisor Professor Xu-Feng Huang
Judith Carrall
Designing tumour-targeting arsenic anti-cancer agents
Primary Supervisor Dr Carolyn Dillon
Licai Cheng
The regulation of central leptin signalling by distinct fatty acids
Primary Supervisor Professor Xu-Feng Huang
Dezerae Cox
The role of the small heat shock proteins in preventing alpha-synuclein aggregation associated with disease
Primary Supervisor Associate Professor Heath Ecroyd
Sarah Crennan
Improving the immune health of preterm infants using novel fatty acids
Primary Supervisor Professor Xu-Feng Huang
David De Oliveira
Understanding the role of streptococcal M protein in invasive disease
Primary Supervisor Dr Martina Sanderson-Smith
Michael De Santis
Understanding the mechanisms of functionally selective antipsychotic drugs and Aripiprazole
Primary Supervisor Professor Chao Deng
Dzung Do-Ha
Non-cell autonomous mechanisms of neurodegeneration in motor neurone disease / amyotrophic lateral sclerosis
Primary Supervisor Dr Lezanne Ooi
Amy Geddes
Does early developmental disruption make the brain more vulnerable to the effects of cannabis?
Primary Supervisor Professor Xu-Feng Huang
Yi Sing Gee
Synthesis of LSD1 inhibitors and the synthesis and reactivity of N-substitututed cyclopropanes
Primary Supervisor Dr Christopher Hyland
Nicholas Geraghty
Exploring the roles of purinergic signalling in inflammatory disorders
Primary Supervisor Associate Professor Ronald Sluyter
Thomas Griffiths
Understanding the bioluminescence mechanism of marine luciferases
Primary Supervisor Dr Haibo Yu
Nathanial Harris
Deciphering the role of SerpinB2 in cancer growth and metastasis
Primary Supervisor Professor Marie Ranson
Emma Hawksworth
Evaluation of the anti-cancer activity of Bismuth(III) complexes
Primary Supervisor Dr Carolyn Dillon
Meng He
Schizophrenia: Control of weight gain and metabolic disorders associated with antipsychotic therapy
Primary Supervisor Professor Xu-Feng Huang
Han Ho
Visualization of DNA repair in live cells at the single-molecule level
Primary Supervisor Professor Antoine van Oijen
Tiantian Jin
Lupane triterpenes and derivatives prevents development of obesity and diabetes via suppressing protein-tyrosine phosphatase 1B (PTP1B) as an allosteric inhibitor in silico, in vitro and in vivo
Primary Supervisor Professor Xu-Feng Huang
Blagojce Jovcevski
Using native mass spectrometry to examine the structure-function relationship of small heat shock proteins
Primary Supervisor Associate Professor Heath Ecroyd
Isabella Lambert Smith
Are proteostasis defects responsible for Amyotrophic Lateral Sclerosis
Primary Supervisor Dr Justin Yerbury
Hoang Lan Chi Dinh
The role of NF-kB signalling during obesity-induced inflammation
Primary Supervisor Professor Xu-Feng Huang
Joshua Leite
The roles of muscarinic M3 receptors in antipsychotic-induced glucometabolic side-effects
Primary Supervisor Professor Chao Deng
Jiamei Lian
The mechanisms for preventing and treating Olanzapine-induced obesity with betahisitine: Implications for clinical medication
Primary Supervisor Professor Chao Deng
Jeremy Lum
Novel antipsychotics in the treatment of schizophrenia
Primary Supervisor Professor Xu-Feng Huang
Diane Ly
Bacterial subversion of the plasminogen activation system in the early stages of disease
Primary Supervisor Dr Martina Sanderson-Smith
Amy McGrath
The β-sliding clamp as a target for new antimicrobial drugs
Primary Supervisor Associate Professor Aaron Oakley
Enrico Monachino
The effects of DNA-protein roadblocks on DNA replication
Primary Supervisor Professor Antoine van Oijen
Varsha Natarajan
Single-molecule studies of the eukaryotic replisome
Primary Supervisor Professor Antoine van Oijen
Ashleigh Osborne
Therapeutic efficacy of cannabidiol on cognitive function and the underlying mechanisms
Primary Supervisor Dr Katrina Green
Bo Pan
The functionally selective effects of aripiprazole at the mesolimbic and nigrostriatal dopaminergic pathways
Primary Supervisor Professor Chao Deng
Melanie Pearsall
Transition-metal catalysed radiolabelling reaction development and synthesis of heterocycles from cyclopropenes
Primary Supervisor Dr Christopher Hyland
Jay Perry
Understanding the biology of metastatic cutaneous squamous cell carcinoma
Primary Supervisor Professor Marie Ranson
Ranjith Raj
The effects of antipsychotic treatment on the binding density of adrenergic receptors in the rat brain
Primary Supervisor Professor Chao Deng
Dan Rivinoja
Dearomatisation reactions for the synthesis of novel heterocycles
Primary Supervisor Dr Christopher Hyland
Kate Roberts
Investigating the role of SOD1 in neuro-inflammation in Amyotrophic Lateral Sclerosis
Primary Supervisor Dr Justin Yerbury
Anthea Rote
The effect of disease-related mutations on the structure and function of the small heat shock molecular chaperone protein Hsp27
Primary Supervisor Associate Professor Heath Ecroyd
Rebecca San Gil
The mechanism and activation of the heat shock response in neurons
Primary Supervisor Associate Professor Heath Ecroyd
Sonia Sanz Munoz
Investigating APOE-dependent genetic risk for Alzheimer's disease
Primary Supervisor Dr Lezanne Ooi
Peta Snikeris
Schizophrenia and the immune system: ‘Messed-up’ through the PI3K/Akt pathway
Primary Supervisor Professor Xu-Feng Huang
Lisanne Spenkelink
Visualization of exchange dynamics in the replisome
Primary Supervisor Professor Antoine van Oijen
Bhavaniprasad Vipperla
Computational studies on the mechanisms of the O-GlcNAc transfer by O-GlcNAc transferase
Primary Supervisor Dr Haibo Yu
Heema Vyas
Developing more effective topical antimicrobial preparations for the treatment of biofilm associated skin infections
Primary Supervisor Dr Jason McArthur
Jennifer West
Structural and functional studies of new extracellular chaperones
Primary Supervisor Senior Professor Mark Wilson
Daniel Whiten
Clusterin: its role in motor neurone disease
Primary Supervisor Senior Professor Mark Wilson
Jonathan Williams
Subversion of cell-death mechanisms in invasive bacterial disease
Primary Supervisor Dr Martina Sanderson-Smith
Yizhen Wu
The role of hypothalamic AMPK signalling in central leptin resistance in diet-induced obesity and the regulation by triterpenoids
Primary Supervisor Professor Xu-Feng Huang
Kela Xiao
Understanding the catalytic mechanisms of glycoside hydrolases
Primary Supervisor Dr Haibo Yu
JieXiang Yin
Development of organotransition metal-catalysed reactions for the synthesis and reactivity of small molecules
Primary Supervisor Dr Christopher Hyland
Farzad Zamani
Synthesis and reactivity of highly functionalised allenes
Primary Supervisor Dr Christopher Hyland
Rafaa Zeineddine
The prion-like action of disease proteins in Amyotrophic Lateral Sclerosis: An infectious idea
Primary Supervisor Dr Justin Yerbury
Fanyu Zhang
Development of microemulsion formulations for the transdermal delivery of antimicrobial compounds
Primary Supervisor Dr Jason McArthur