The molecular life sciences have experienced considerable growth as a UOW research strength over the past decade. This growth, coupled with the establishment of Health and Wellbeing initiative as a broader strategic direction for the University, catalysed an $80 million UOW investment into Molecular Horizons, a new molecular life sciences research Institute.
Our impact
A message from the Director
"Critical to Molecular Horizon's vision is the systematic integration of cutting-edge visualisation techniques spanning from the molecular to the organismal scale with mechanistic biology and medicinal chemistry. These enabling technologies will allow transformative understanding of the molecular principles of disease and utilisation of that knowledge to identify strategies to develop novel therapeutics and diagnostics.
The 2019-2020 period brought a number of major milestones for Molecular Horizons. With our new, 6,500-m2 world-class research facility having reached completion in January 2020, our teams were eager to recommence their research and put to use the new equipment – including the brand new cryo-EM facility with its state-of-the-art equipment to determine the atomic-level structures of biological macromolecules.
Little did we know that we would be opening our Institute at the brink of a global pandemic. There is no doubt that 2020 was a disruptive and challenging year. The impact of the COVID-19 pandemic on our lives started a process that saw the world changed in many ways. With our colleagues and students living in periods of extended lockdowns, teaching staff facilitating the transition of all UOW’s teaching to online platforms, colleagues feeling the financial realities of the university environment during COVID, adapting to new COVID-safe practices, and juggling the consequential mental pressures, adjusting to the new normal impacted us all.
Despite the new challenges we were facing, Molecular Horizons has demonstrated an excellent few years of impactful research and wonderful highlights, all described in this report. In the 2019-2020 period alone, our researchers have been awarded over 90 grants and have published more than 340 publications. Some other notable achievements include the prestigious fellowships, scientific awards and many other accolades that are a testament to the exceptional talent within our Institute.
Molecular Horizons partners with industry, government, universities and community partners to cultivate highly integrated research programs that transcend traditional, individual project-based efforts, to deliver outcomes of increased scale, scope and impact. Underpinned by a strong institutional culture of creativity, innovation and collegiality our mission is to translate basic molecular understanding into real-world applications and, in doing so, recruit and train the next generation of interdisciplinary life scientists.
In this highly multidisciplinary environment, Molecular Horizons members have provided joint supervision of Honours and HDR students, coordinated exchange programs, co-authored publications and grants, and successfully graduated over 50 postgraduate students in the 2019-2020 period, many with awards, prizes, and first author publications in high-impact journals.
Lastly, I would like to acknowledge and thank all staff and student members for their resilience, endurance and exceptional strength that has been shown in abundance during this time. We should be extremely proud of the quality of our research whilst navigating the obstacles the pandemic created in all aspects of our lives. Also, I would like to thank all our partners for helping us grow as an Institute. In particular, I am grateful for our generous donors joining and supporting us on this exciting journey. It is my pleasure to celebrate with you a wonderful first two years of Molecular Horizons."
Distinguished Professor Antoine van Oijen
Director, Molecular Horizons
The transformational research of Molecular Horizons is underpinned by offering internal and external researchers access to world-class research infrastructure. High-end core facilities are key drivers of the mission of Molecular Horizons, providing opportunities for cutting-edge and collaborative research. In doing so, this state-of-the-art infrastructure lies at the heart of the Molecular Horizons vision “that seeing is believing".
Our impact
Developing anti-cancer drugs with industry
Molecular Horizons researcher Dr Carolyn Dillon and her research team have entered a joint venture licencing agreement with the Australian Pharmaceutical Company, Phebra. The agreement stems from an ongoing UOW/Phebra relationship that was established in 2016 following Dr Dillon’s conception of a class of arsenic compounds that selectively target specific cancers.
The concept was patented internationally in 2019 and Phebra has funded further patents across the Americas, Asia, Europe and the Middle East. The collaboration utilises the expertise of Dr Dillon’s research group in the areas of synthesis, characterisation, purification and in vitro biological testing to design and identify candidates for in vivo assessment. The most promising compound, to date, targets and kills leukemia cells over healthy blood cells with one thousand times greater selectivity.
The collaboration provides invaluable insight into the development and manufacturing of drugs by the pharmaceutical industry for postgraduate and undergraduate medicinal chemistry students at UOW.
Microprobe XRF imaging showing arsenic uptake and distribution throughout both the cytoplasm and nucleus of a leukemia cell following treatment with the potential arsenic drug.
Industry projects
- Grünenthal (through Uniquest): $1.2M (2019-2020) to D/Prof David Adams
Development of peptide therapeutics
- GenieUs Genomics: $511k (2019-2020) to A/Prof Lezanne Ooi
Tarantino Project – Reprogramming fibroblasts into induced pluripotent stem cells
- Phebra Pharmaceutical Development and Manufacturing: $213k to Dr Carolyn Dillon
Synthesis and biological assessment of Arsenic-based leukemia and pancreatic homing complexes
- US Army Medical Research: $118k to S/Prof Mark Wilson and Prof Heath Ecroyd
Rapid Flow Cytometry Screen for Identifying Novel ALS Drug Leads
- DSM Nutritional Products: $100k (2019) to Prof Barbara Meyer
Can Omega3 and/or Multivitamins & Mineral Supplementation Enhance Behavioural Self-control
We gratefully acknowledge the individuals and organisations that donated to Molecular Horizons in 2019 and 2020. COVID-19 made 2020 a challenging year, but it is in large part due to our meaningful community connections that we were able to continue to empower and support our researchers. Those donations have allowed us to provide our junior researchers with the extra support that has proven so critical in times of uncertainty and reduced government funding. It demonstrates the power of working together with the community to do high-impact research and fuel the breakthroughs that can change lives.
In appreciation
A special thank you to the following individuals for their generosity:
- Madeline Tynan and family ($66,000)
- Professor Bruce Warren ($38,000)
- And our anonymous donors ($300,000)
Michael Tynan Challenge
The Michael Tynan Challenge (MTC) was created in dedication of Michael Tynan, OAM, who sadly passed away in February 2016 after a two-year fight with cancer. It was Michael’s dedication to community and family that inspired his daughter, Tynan Motors Group Director Madeline Tynan, to establish the MTC in 2016. The MTC’s goal is to raise funds that contribute to medical health research that will save lives and create better health outcomes within the community.
We are incredibly honoured and grateful to be invited to participate in the various fundraiser activities set out by the MTC throughout the year, including the Race Day Luncheon and the Coastal Walk Challenge. The funds raised from these activities have enabled us to establish scholarships supporting undergraduate students during their fourth-year honours projects. Embedded in the research groups in Molecular Horizons, these students use the final year of their studies to conduct impact-driven research that contributes to solving global health challenges such as motor neurone disease, Alzheimer’s, cancer therapeutics, molecular neuroscience and protein aggregation related diseases. During 2019 and 2020, we have been able to support 11 students with a Tynan Family Molecular Horizons Honours Scholarship.
"As a family, we are passionate about giving back to the community that supports our family business."
"We are delighted to support the development taking place in the medical research facilities at UOW, which is assisting not only the local but broader community, especially at a time when the importance of medical research is so evident today, during this epidemic, for both physical and mental health." - Madeline Tynan
The Centre for Oncology Education & Research Translation (CONCERT)
CONCERT was established in 2014 as part of the Cancer Institute NSW (CINSW) initiative for Translational Cancer Research Centres (TCRC). CONCERT brought together the knowledge and expertise of cancer health professionals & researchers from 10 institutions and 3 local health districts hospitals across Sydney and the Illawarra/Shoalhaven to facilitate translation of cancer research to achieve better outcomes for those affected by cancer. CONCERT has recently transitioned into a new larger entity called the Sydney Partnership for Health, Education, Research and Enterprise (SPHERE) Cancer Clinical Academic Group (CAG), which was recently awarded a $7million Translational Cancer Research Capacity Building Grant from Cancer Institute NSW. During its 7 years of operation CONCERT became a 370 member strong cancer research network with overarching Targets and Therapeutics (coordinated by Prof Ranson from MH/IHMRI who has also acted as Deputy Director of CONCERT) and Policy and Practice flagship programmes. This includes the ongoing CONCERT Biobank which has collected over 35,000 samples for over 40 research projects to date. There is now a fully developed process for routine patient sample collection and analysis within the Illawarra and across the CONCERT network, with firm research links established to other clinical and academic institutes in NSW. The access to patient samples with linked clinical data is informing biomarker discovery for diagnostic, prognostic and/or predictive (e.g., drug responsiveness) analyses. For example, we established patient-derived cultures from gastric cancer circulating tumour cells as avatars for drug responsiveness studies in this disease.
Fluorescence microscopy image of patient-derived gastric cancer circulating tumour cells showing staining for DNA (DAPI, blue) and the cellular structural component Actin (red). These cells are also highly positive for the cell surface growth factor receptor EGFR (green), whose overexpression is often a feature of rapidly growing and invasive cancer cells. Drugs blocking EGFR can be used to limit gastric cancer spread.
- Australian Research Council Industrial Transformation Training Centre for Cryo-EM on Membrane Proteins (CCeMMP): Monash University, University of Melbourne, WEHI, University of Wollongong (2020)
- Wollongong Antimicrobial Resistance Research Alliance (WARRA): Illawarra Shoalhaven Health District, NSW Health Pathology, Southern.IML/Sonic, University of Wollongong (2019-2020)
- Centre for Oncology Education & Research Translation (CONCERT): UNSW, Western Sydney University, Ingham Institute for Applied Medical Research, South Western Sydney Local Health District, Illawarra Shoalhaven Local Health District, Illawarra Health and Medical Research Institute, Health Directorate ACT Government, Australian National University, University of Canberra, University of Wollongong (2019-2020)
- The Australian Characterisation Commons at Scale (ACCS): Monash University: AARNet, Bioplatforms Australia, Flinders University, EMBL Australia, Microscopy Australia, National Imaging Facility, Pawsey Supercomputing Centre, QCIF, RMIT University, Swinburne University, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, University of New South Wales, University of Queensland, University of South Australia, University of Sydney, University of Western Australia, University of Wollongong (2020)
Hand sanitiser to protect local healthcare workers
Molecular Horizons and Illawarra Shoalhaven Local Health District join forces to bolster local hand sanitiser stocks Critical shortages of medical supplies have been a worldwide problem in the fight against the COVID-19 pandemic. But experts in the Illawarra have come up with their own solution.
Read more
Where are they now?
Our students and their journeys
Dr San Gil was awarded a PhD from the University of Wollongong in 2018. Her PhD research was done in Molecular Horizons under the primary supervision of Prof Heath Ecroyd and co-supervised by A/Prof Lezanne Ooi and Prof Justin Yerbury. Together, they discovered that neurodegenerative disease-associated stresses escape the detection of protective responses in brain cells, leaving them susceptible to cell death. Dr San Gil travelled to London in 2016 to undertake an Endeavour Research Fellowship at the Institute of Neurology, University College London. Recently, she was appointed as the inaugural Fight MND Early Career Research Fellow at the Queensland Brain Institute, University of Queensland, where Dr San Gil works in Dr Adam Walker’s laboratory. In this position, she is working towards advancing our understanding of the genes and biological processes driving protein aggregation and neurodegeneration in motor neuron disease.
Dr Kimberley Davis completed her PhD in 2015 in what was then the UOW School of Chemistry, under the supervision of Molecular Horizons researchers Prof Stephen Ralph, Prof Jenny Beck and Dr Chris Richardson. Although a chemist by background, Dr Davis was able to branch out into the biomolecular sphere, investigating how a range of nickel Schiff base complexes she synthesised interacted with Quadruplex DNA, a structure which is implicated in tumour immortality.
Since then, Dr Davis has worked in a diverse range of areas – science communication, academic teaching, lab-based work, and community engagement. Dr Davis: ‘Some of these appear to have no relation to my PhD! However, I can safely say that a PhD isn’t just about domain knowledge; you learn a great many more things, but most of all how to adapt and how to continuously learn.’
Dr Davis has now moved into the Clinical Research sphere, as part of the Research Operations team for the Illawarra Shoalhaven Local Health District, joining in mid-2020. Despite having no clinical background, she has been able to readily transition into this space, working with clinicians in a range of disciplines and assisting with their projects – very much like an all-areas Clinical Post-Doc. She has already published with ISLHD clinicians in both General and Orthopaedic surgery, and is currently working on papers for Aged Care and Emergency Stroke assessment, as well as being involved in projects in areas such as Health Information Management, Pharmacy, Cardiology, Cancer prognostics, and much more.
Dr Sandeep Satapathy received his PhD based on work with Molecular Horizons researcher Prof Mark Wilson. His research project was based on understanding the structure-function relationship of secreted chaperones, proteins that guard the folding and stability of other proteins. During his PhD he has successfully established the first rapid and high-yield mammalian expression system of the very difficult to express protein clusterin and establish a detailed understanding of the role of clusterin in intracellular protein quality control. Subsequently, he was awarded a Harvard Post-Doctoral Research Fellowship, allowing Dr Satapathy to work in world-class labs in the Blavatnik Institute of Cell Biology at Harvard Medical School and The Broad Institute. Expanding on his research interests in understanding the biological roles of the secretome, his current work is focused on the role of secretory proteins in the molecular regulation of pancreatic beta cells. As a trained cell and molecular biologist, Dr Satapathy enjoys asking questions and finding meaningful answers to the signaling and molecular crosstalk of proteins associated with serious human diseases like Alzheimer’s disease and diabetes.
Highlights
Mapping dynamic lipid biochemistry with high spatial and molecular detail
Noteable achievements
- Awards
- Grant and fellowship highlights
- Grants 2016-2020
- HDR completions
- Selected publications
- Publications (2020)
- Publications (2019)
- 2019 NSW Tall Poppy Award: Dr Natalie Matosin
- 2019 Wollongong Citizen of the Year: Prof Justin Yerbury
- 2020 Rebecca L Cooper Memorial Award: Dr Natalie Matosin
- 2020 UOW Vice-Chancellor’s Research Excellence Award for Emerging Researcher: Dr Yee Lian Chew
- 2020 Margaret Sheil Leadership Award (Royal Australian Chemical Institute): A/Prof Danielle Skropeta
- 2020 NSW Premier’s Prize for Science and Engineering (Medical Biological Sciences): D/Prof Antoine van Oijen
- 2020 Order of Australia: Prof Justin Yerbury
- 2020 NSW Master Builder Award (Excellence in Construction): Paul Wellings Building
- 2019 National Institutes of Health (USA) Program Grant to D/Prof Antoine van Oijen, Dr Andrew Robinson and Dr Harshad Ghodke (in collaboration with University of Wisconsin, Madison and University of Southern California) ($1.5M to Molecular Horizons)
‘Creation and Repair of Postreplicative DNA Gaps’ - 2019 ARC Future Fellowship to Dr Shane Ellis ($734k)
‘Mapping dynamic lipid biochemistry with high spatial and molecular detail’ - 2019 Cancer Council project grant to Dr Debbie Watson ($448k)
‘Immune Cell Depletion and P2X7 Receptor Blockade to Prevent Graft-versus-host Disease in Blood Cancer Treatment’ - 2019 MRFF Frontier Stage 1 funding to multi-organisation consortium co-led by D/Prof Antoine van Oijen ($1M)
‘Use of disruptive technologies to trace, track and tackle antibiotic resistance’ - 2019 Department of Defense (USA) Idea Award to S/Prof Mark Wilson and Prof Heath Ecroyd (in collaboration with University of Queensalnd and Macquarie University) ($339k to Molecular Horizons)
‘Rapid Flow Cytometry Screen for Identifying Novel ALS Drug Leads’ - 2020 ARC Discovery Project to Prof Adam Trevitt ($420k)
‘New laser and mass spectrometry methods for detecting protonation isomers’ - 2020 NHMRC Investigator grant to D/Prof Xu-Feng Huang ($1.5M)
‘Neurite deficits, obesity and cortical thinning: Prevention and treatment in schizophrenia’ - 2020 NHMRC Investigator grant to Dr Yee-Lian Chew ($640k)
‘Investigating neuroendocrine dysregulation as new targets for chronic pain management’ - 2020 NHMRC Ideas grant to Dr Gokhan Tolun ($636k)
‘Revealing the molecular mechanistic details of viral DNA recombination towards developing novel anti-viral drugs’ - 2020 ARC Industrial Transformation Training Centre funding to D/Prof David Adams and D/Prof Antoine van Oijen (in collaboration with Monash University, University of Melbourne and WEHI) ($809k to Molecular Horizons)
‘ARC Training Centre for Cryo-electron microscopy of membrane proteins for drug discovery – CCEMMP’
*Grants received at $100,000 or more
National Health and Medical Research Council (NHMRC)
Neurite deficits, obesity and cortical thinning: Prevention and treatment in schizophrenia
Xu-Feng Huang (SMAH) - Staff (Chief Investigator)
$1,500,000
Australian Research Council (ARC)
ARC Training Centre for Cryo-electron microscopy of membrane proteins for drug discovery - CCEMMP
Antoine van Oijen (SMAH) - Staff (Chief Investigator), David Adams (SMAH) - Limited Term (General) (Chief Investigator)
$809,417
Australian Research Council (ARC)
Mapping dynamic lipid biochemistry with high spatial and molecular detail
Shane Ellis (SMAH) - Staff (Chief Investigator)
$734,162
National Health and Medical Research Council (NHMRC)
Neuronal membranes and connections in dementia: targets for intervention
Lezanne Ooi (SMAH) - Staff (Fellow Other)
$720,144
National Health and Medical Research Council (NHMRC)
Investigating neuroendocrine dysregulation as new targets for chronic pain management
Yee Lian Chew (SMAH) - Staff (Chief Investigator)
$639,750
National Health and Medical Research Council (NHMRC)
Revealing the molecular mechanistic details of viral DNA recombination towards developing novel anti-viral drugs
Gokhan Tolun (SMAH) - Staff (Chief Investigator), Antoine van Oijen (SMAH) - Staff (Chief Investigator)
$636,368
National Health and Medical Research Council (NHMRC)
Exposures of mobile phone radiofrequency electromagnetic energy in juveniles: effects on brain development and behaviours
Chao Deng (SMAH) - Staff (Chief Investigator), Rodney Croft (ASSH) - Staff (Chief Investigator)
$632,100
National Health and Medical Research Council (NHMRC)
Repurposing Amiloride into Breast Cancer Drugs with a Dual-Targeting Mechanism
Michael Kelso (SMAH) - Staff (Chief Investigator), Marie Ranson (SMAH) - Staff (Chief Investigator)
$606,966
National Health and Medical Research Council (NHMRC)
Understanding the mechanisms for ameliorating/preventing antipsychotic-induced obesity in early life
Chao Deng (SMAH) - Staff (Chief Investigator), Jiamei Lian (SMAH) - Staff (Chief Investigator)
$576,496
Human Frontier Science Program
High-throughput single-molecule evolution
Antoine van Oijen (SMAH) - Staff (Chief Investigator)
$545,663
Australian Research Council (ARC)
Molecular Interactions with an Antibiotic Target in DNA Replication
Nicholas Dixon (SMAH) - Staff (Chief Investigator), Aaron Oakley (SMAH) - Staff (Chief Investigator), Andrew Robinson (SMAH) - Staff (Chief Investigator), Michael Kelso (SMAH) - Staff (Chief Investigator)
$534,573
Australian Research Council (ARC)
A functional dissection of the bacterial replisome
Antoine van Oijen (SMAH) - Staff (Chief Investigator), Nicholas Dixon (SMAH) - Staff (Chief Investigator)
$524,298
National Health and Medical Research Council (NHMRC)
From lead compounds to potential therapeutics: Drugs to treat Clostridium Difficile Infections
Stephen Pyne (SMAH) - Staff (Chief Investigator), Paul Keller (SMAH) - Staff (Chief Investigator)
$523,460
Australian Research Council (ARC)
Defining systems that clear dangerous misfolded proteins from body fluids
Mark Wilson (SMAH) - Staff (Chief Investigator), Heath Ecroyd (SMAH) - Staff (Chief Investigator)
$452,800
Cancer Council
Immune Cell Depletion and P2X7 Receptor Blockade to Prevent Graft-versus-host Disease in Blood Cancer Treatment
Debbie Watson (SMAH) - Staff (Chief Investigator)
$448,365
Australian Research Council (ARC)
New laser and mass spectrometry methods for detecting protonation isomers
Adam Trevitt (SMAH) - Staff (Chief Investigator)
$420,000
Australian Research Council (ARC)
Shared Picosecond-Laser Facility
Adam Trevitt (SMAH) – Staff (Chief Investigator), Attila Mozer (AIIM) - Staff (Chief Investigator)
$417,900
National Institute of Health (NIH)
Creation and Repair of Postreplicative DNA Gaps
Antoine van Oijen (SMAH) - Staff (Chief Investigator), Harshad Ghodke (SMAH) - Staff (Fellow Other), Andrew Robinson (SMAH) - Staff (Chief Investigator), Nicholas Dixon (SMAH) - Staff (Chief Investigator)
$379,914
Health Research Council of New Zealand (HRC)
Repurposing Amiloride Derivatives as New Agents for Drug-Resistant Tuberculosis
Michael Kelso (SMAH) - Staff (Chief Investigator)
$364,077
Australian Research Council (ARC)
A New Molecular Platform for Catalytic Synthesis of Heterocycles
Stephen Pyne (SMAH) - Staff (Chief Investigator), Christopher Hyland (SMAH) - Staff (Chief Investigator)
$357,072
Australian Research Council (ARC)
Superresolution fluorescence imaging in microbiology
Antoine van Oijen (SMAH) - Staff (Chief Investigator), Nicholas Dixon (SMAH) - Staff (Chief Investigator)
$355,000
National Health and Medical Research Council (NHMRC)
Antibiotic resistance: combining microscopy, microfluidics and genomics to target bacterial DNA repair pathways
Andrew Robinson (SMAH) - Staff (Chief Investigator), Antoine van Oijen (SMAH) - Staff (Chief Investigator), Harshad Ghodke (SMAH) - Staff (Associate Investigator), Spyridon Miyakis (SMAH) - Staff (Associate Investigator), Peter Newton (SMAH) - Honorary Fellow (Associate Investigator)
$352,859
Nanoparticle-Mediated Gene Delivery of Frataxin to Neurons
Mirella Dottori (SMAH) - Staff (Chief Investigator)
$341,763
National Health and Medical Research Council (NHMRC)
Blood group antigen recognition by Group A Streptococcus mediates host colonisation
Martina Sanderson-Smith (SMAH) - Staff (Chief Investigator)
$340,821
Department of Defence (DoD)
Rapid Flow Cytometry Screen for Identifying Novel ALS Drug Leads
Mark Wilson (SMAH) - Staff (Chief Investigator), Heath Ecroyd (SMAH) - Staff (Chief Investigator)
$339,360
National Health and Medical Research Council (NHMRC)
The role of mutant cyclin F in amyotrophic lateral sclerosis
Justin Yerbury (SMAH) - Staff (Chief Investigator), Lezanne Ooi (SMAH) - Staff (Chief Investigator)
$331,483
National Health and Medical Research Council (NHMRC)
Early antipsychotic exposure during childhood and adolescence: Does it lead to long term brain and behaviour changes in adulthood?
Jiamei Lian (SMAH) - Staff (NHMRC Early Career Fellowship)
$318,768
National Health and Medical Research Council (NHMRC)
Early antipsychotic exposure during childhood and adolescence: Does it lead to long term brain and behaviour changes in adulthood?
Jiamei Lian (SMAH) - Staff (NHMRC Early Career Fellowship)
$318,768
Australian Research Council (ARC)
ARC Research Hub for Australian Steel Innovation
Paul Zulli (EIS) - Staff (Chief Investigator), Brian Monaghan (EIS) - Staff (Chief Investigator), Jason Hodges (EIS) - Faculty Honorary Fellow (Partner Investigator), Sheng Chew (EIS) - Faculty Honorary Fellow (Partner Investigator), Lip Teh (EIS) - Staff (Chief Investigator), Prabuono Kosasih (EIS) - Staff (Chief Investigator), Stephen Van Duin (EIS) - Staff (Chief Investigator), Christopher Richardson (SMAH) - Staff (Chief Investigator), Paul Cooper (EIS) - Staff (Chief Investigator), Elena Pereloma (EIS) - Staff (Chief Investigator), Huijun Li (EIS) - Staff (Chief Investigator), David Pinson (EIS) - Faculty Honorary Fellow (Partner Investigator), Yue Zhao (EIS) - Staff (Chief Investigator), Azdiar Gazder (AIIM) - Staff (Chief Investigator), William Scott (EIS) - Staff (Chief Investigator)"
$316,563
Australian Research Council (ARC)
Electrophysiology Facility for Cell Phenotyping and Drug Discovery
David Adams (SMAH) - Limited Term (General) (Chief Investigator), Jeremy Crook (AIIM) - Staff (Chief Investigator), Lezanne Ooi (SMAH) - Staff (Chief Investigator), Robert Kapsa (AIIM) - Staff (Chief Investigator)
$284,656
Australian Research Council (ARC)
New photoinitiators and polymers for tack-free LED cured surface coatings
Paul Keller (SMAH) - Staff (Chief Investigator), Adam Trevitt (SMAH) - Staff (Chief Investigator), Dianne Jolley (SMAH) - Staff (Chief Investigator)
$230,000
National Health and Medical Research Council (NHMRC)
Structure and function of a cancer-linked co-regulator complex
Antoine van Oijen (SMAH) - Staff (Chief Investigator)
$213,748
National Health and Medical Research Council (NHMRC)
Building an immunocompetent Alzheimer's disease brain-on-a-chip
Lezanne Ooi (SMAH) - Staff (Chief Investigator)
$202,884
Motor Neurone Disease Research Institute Australia
Proteome homeostasis dysfunction in axon terminals as a cause of MND
Justin Yerbury (SMAH) - Staff (Chief Investigator), Lezanne Ooi (SMAH) - Staff (Chief Investigator)
$201,000
National Health and Medical Research Council (NHMRC)
Cutaneous Squamous Cell Carcinoma: defining prognostic markers of metastasis
Marie Ranson (SMAH) - Staff (Chief Investigator), Bruce Ashford (SMAH) - Staff (Chief Investigator)
$199,208
NSW Health
Role of the intrinsic cardiac nervous system in myocardial ischaemia and arrhythmias
David Adams (SMAH) - Limited Term (General) (Chief Investigator), Alexander Harper (SMAH) - Faculty Honorary Fellow (Investigator), Leonard Arnolda (SMAH) - Staff (Investigator)
$185,905
University Of Wollongong
The IVIS SpectrumCT preclinical in vivo imaging system
Kara Perrow (SMAH) - Staff (Chief Investigator), Marie Ranson (SMAH) - Staff (Chief Investigator), Mark Wilson (SMAH) - Staff (Chief Investigator), Heath Ecroyd (SMAH) - Staff (Chief Investigator), Ronald Sluyter (SMAH) - Staff (Chief Investigator), Moeava Tehei (EIS) - Staff (Chief Investigator), Carolyn Dillon (SMAH) - Staff (Chief Investigator), Martina Sanderson-Smith (SMAH) - Staff (Chief Investigator), Chao Deng (SMAH) - Staff (Chief Investigator), Lezanne Ooi (SMAH) - Staff (Chief Investigator), Brett Garner (SMAH) - Staff (Chief Investigator), Danielle Skropeta (SMAH) - Staff (Chief Investigator), Zhilian Yue (AIIM) - Staff (Chief Investigator), Phillip Byrne (SMAH) - Staff (Chief Investigator), Kelly Newell (SMAH) - Staff (Chief Investigator)
$183,333
University Of Wollongong
IncuCyte S3 Live-cell imaging and analysis platform with software packages
Xu-Feng Huang (SMAH) - Staff (Chief Investigator), Lezanne Ooi (SMAH) - Staff (Chief Investigator), Chao Deng (SMAH) - Staff (Chief Investigator), David Adams (SMAH) - Limited Term (General) (Chief Investigator), Heath Ecroyd (SMAH) - Staff (Chief Investigator), Kara Perrow (SMAH) - Staff (Chief Investigator), Justin Yerbury (SMAH) - Staff (Chief Investigator), Katrina Green (SMAH) - Staff (Chief Investigator), Nadia Solowij (ASSH) - Staff (Chief Investigator), Zhilian Yue (AIIM) - Staff (Chief Investigator), Konstantin Konstantinov (AIIM) - Staff (Chief Investigator), Kelly Newell (SMAH) - Staff (Chief Investigator), Mark Wilson (SMAH) - Staff (Chief Investigator), Haibo Yu (SMAH) - Staff (Chief Investigator)
$176,707
National Health and Medical Research Council (NHMRC)
The role of mutant CYLD in frontotemporal dementia and motor neuron disease
Lezanne Ooi (SMAH) - Staff (Chief Investigator)
$170,999
Australian Research Council (ARC)
Pluses and minuses of lipid mass spectrometry
Todd Mitchell (SMAH) - Staff (Chief Investigator)
$163,750
University Of Wollongong
Ultra Performance Liquid Chromatography-Mass Spectrometry for Chiral and Achiral Analysis
Danielle Skropeta (SMAH) - Staff (Chief Investigator), Stephen Pyne (SMAH) - Staff (Chief Investigator), Paul Keller (SMAH) - Staff (Chief Investigator), Michael Kelso (SMAH) - Staff (Chief Investigator), Christopher Hyland (SMAH) - Staff (Chief Investigator), Celine Kelso (SMAH) - Staff (Chief Investigator), Carolyn Dillon (SMAH) - Staff (Chief Investigator), Christopher Richardson (SMAH) - Staff (Chief Investigator), Yusuke Yamauchi (AIIM) - Staff (Chief Investigator), Dianne Jolley (SMAH) - Staff (Chief Investigator), Barbara Meyer (SMAH) - Staff (Chief Investigator), Marie Ranson (SMAH) - Staff (Chief Investigator), Kara Perrow (SMAH) - Staff (Chief Investigator)
$161,538
University Of Wollongong
Single Crystal X-ray Crystallography for the Structure Determination of Molecules and Materials at UOW
Christopher Richardson (SMAH) - Staff (Chief Investigator), Stephen Pyne (SMAH) - Staff (Chief Investigator), Paul Keller (SMAH) - Staff (Chief Investigator), Stephen Ralph (SMAH) - Staff (Chief Investigator), Michael Kelso (SMAH) - Staff (Chief Investigator), Danielle Skropeta (SMAH) - Staff (Chief Investigator), Aaron Oakley (SMAH) - Staff (Chief Investigator), Christopher Hyland (SMAH) - Staff (Chief Investigator), Carolyn Dillon (SMAH) - Staff (Chief Investigator), David Officer (AIIM) - Staff (Chief Investigator), Gerhard Swiegers (AIIM) - Staff (Chief Investigator), Pawel Wagner (AIIM) - Staff (Chief Investigator), Zhenguo Huang (AIIM) - Staff (Chief Investigator), David Wexler (AIIM) - Staff (Chief Investigator), David Wexler (EIS) - Staff (Chief Investigator)
$159,326
National Health and Medical Research Council (NHMRC)
Harnessing the human postmortem brain to elucidate changes in FK506 binding protein (FKBP5) in the neuropathology of severe psychiatric disorders
Natalie Matosin (SMAH) - Student (NHMRC Early Career Fellowship)
$158,596
National Health and Medical Research Council (NHMRC)
Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE): Quality and safety in the implementation of medicinal cannabis use in the community
Nadia Solowij (ASSH) - Staff (Chief Investigator), Xu-Feng Huang (SMAH) - Staff (Chief Investigator), Kathleen Eagar (BAL) - Staff (Chief Investigator)
$158,553
National Health and Medical Research Council (NHMRC)
Anti-sporulation strategies for Clostridium difficile infections
Stephen Pyne (SMAH) - Staff (Chief Investigator), Paul Keller (SMAH) - Staff (Chief Investigator), Haibo Yu (SMAH) - Staff (Chief Investigator)
$157,673
Cancer Institute NSW
Reducing the Morbidity of Head and Neck Cancer Treatment
Bruce Ashford (SMAH) - Staff (Chief Investigator), Marie Ranson (SMAH) - Staff (Chief Investigator), Gordon Wallace (AIIM) - Staff (Chief Investigator)
$143,333
Cancer Australia
Implantable drug-eluting device: localised drug delivery for non-resectable pancreatic cancer
Kara Perrow (SMAH) - Staff (Chief Investigator), Morteza Aghmesheh (SMAH) - Honorary Fellow (Chief Investigator)
$139,719
University Of Wollongong
Influences and barriers to responsible use of antibiotics: The 21st century health challenge
Christopher Degeling (ASSH) - Staff (Chief Investigator), Mitchell Byrne (ASSH) - Staff (Chief Investigator), Antoine van Oijen (SMAH) - Staff (Chief Investigator)
$116,667
Motor Neurone Disease Research Institute Australia
Astrocytic modulation of neuronal excitability and cell death in Motor Neurone Disease
Lezanne Ooi (SMAH) - Staff (Chief Investigator), Justin Yerbury (SMAH) - Staff (Investigator)
$100,000
Rebecca L Cooper Medical Research Foundation
Unravelling the contribution of early life stress to psychopathology - a morphological study
Natalie Matosin (SMAH) - Staff (Chief Investigator)
$100,000
Rebecca L Cooper Medical Research Foundation
Investigating nociceptor sensitisation as a target for chronic pain treatment
Yee Lian Chew (SMAH) - Staff (Chief Investigator)
$100,000
Motor Neurone Disease Research Institute Australia
Targeting cortical hyperexcitability and neurodegeneration in amyotrophic lateral sclerosis
Lezanne Ooi (SMAH) - Staff (Chief Investigator)
$100,000
Timothy Ablott, School of Chemistry and Molecular Bioscience
Supervisor: Doctor Christopher Richardson
Thesis title: Advancing Underexplored Post-Synthetic Chemistry in Metal-Organic Frameworks
Sam Adhikary, School of Chemistry and Molecular Bioscience
Supervisor: Doctor Debbie Watson
Thesis title: Therapeutic Strategies to Prevent Graft-Versus-Host Disease
Ayedh Alqarni, School of Medicine
Supervisor: Professor Barbara Meyer
Thesis title: Investigation of alteration in erythrocyte lipids in people at ultra-high risk of developing psychosis
Umar Ali, School of Chemistry and Molecular Bioscience
Supervisor: Professor Marie Ranson
Thesis title: Characterisation of the Urokinase Plasminogen Activation (uPA) System in the Rat Collagen Induced Arthritis Model: Pharmacological Investigations of Methotrexate and uPA Inhibition
Bruce Ashford, School of Chemistry and Molecular Bioscience
Supervisor: Professor Marie Ranson
Thesis title: The mutational landscape of metastatic cutaneous squamous cell carcinoma
Monique Bax, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Lezanne Ooi
Thesis title: Examination of the Ubiquitin Proteasome System in Induced Pluripotent Stem Cell Derived Motor Neurons, and Related Cell Types in the Context of Amyotrophic Lateral Sclerosis
Lisa Belfiore, School of Chemistry and Molecular Bioscience
Supervisor: Doctor Kara Perrow
Thesis title: Development of Ligand-Directed Drug-Loaded Liposomes to Target Heterogeneous Tumour Cell Populations in Metastatic Breast Cancer
Ronald Brown, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Christopher Hyland
Thesis title: Drug Development for Neglected Diseases and Palladium Catalysis in Reaction Development
Daniel Brungs, School of Chemistry and Molecular Bioscience
Supervisor: Professor Marie Ranson
Thesis title: Molecular and clinical biomarkers in gastrointestinal cancer
Macguire Bryant, School of Chemistry and Molecular Bioscience
Supervisor: Doctor Christopher Richardson
Thesis title: Post-Synthetic Reactivity in Metal-Organic Frameworks
Nicholas Butler, School of Chemistry and Molecular Bioscience
Supervisor: Professor Paul Keller
Thesis title: Old Dye, New Tricks? Diversity-Oriented Synthesis of Heterocycles from Cascade Reactions of Indigo
Judith Carrall, School of Chemistry and Molecular Bioscience
Supervisor: Doctor Carolyn Dillon
Thesis Title: Designing tumour-targeting arsenic anti-cancer agents
Anthony Carroll, School of Chemistry and Molecular Bioscience
Supervisor: Senior Professor Stephen Pyne
Thesis title: Total synthesis of eleven hyacinthacine C-type analogues and the correction of the structures of natural hyacinthacine C1 and C5
Christiana Dawurung, School of Chemistry and Molecular Bioscience
Supervisor: Senior Professor Stephen Pyne
Thesis title: Phytochemical and Biological Studies of Selected Nigerian Traditional Medicinal Plants Used in the Treatment of Diarrhea
Christopher Dobie, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Danielle Skropeta
Thesis title: Rational Design, Synthesis, and Biological Evaluation of Human Sialyltransferase Inhibitors
Melanie Drew, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Christopher Hyland
Thesis title: Gold(I)-Catalysed Reactions of Cyclopropenyl Carbinol Derivatives
Peng Gao, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Haibo Yu
Thesis title: Computer-aided Hydrogen Storage Materials Design: Accurate Predictions of NMR Chemical Shifts and MD Simulation of Nitrogen and Boron Containing Compounds
Jayden Gaston, School of Chemistry and Molecular Bioscience
Supervisor: Professor Paul Keller
Thesis title: Swimming In Chiral Pnictogen Pools - The Exploration of 3-Membered Bicyclic Chiral Pool Intermediates for the Synthesis of Libraries of Chiral 1,2-Dipnictogens
Nicholas Geraghty, School of Chemistry and Molecular Bioscience
Supervisor: Professor Ronald Sluyter
Thesis title: The Role of Purinergic Signalling in Inflammatory Disorders
Julian Harrison, School of Chemistry and Molecular Bioscience
Supervisor: Professor Jenny Beck
Thesis title: An Investigation into the Structure of Protein Toxins of Australian Snake Venoms
Sarah Henrikus, School of Chemistry and Molecular Bioscience
Supervisor: Doctor Andrew Robinson
Thesis title: Following the DNA damage response in Escherichia coli: Single-molecule studies of proteins in live cells
Han Ngoc Ho, School of Chemistry and Molecular Bioscience
Supervisor: Distinguished Professor Antoine van Oijen
Thesis title: Visualisation of Transcription-coupled Repair in Live Eschericha Coli
Venkatasaisandeep Inakollu, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Haibo Yu
Thesis title: Computational vibrational spectroscopic studies for condensed phase systems
Jeremy Lum, School of Medicine
Supervisor: Associate Professor Kelly Newell
Thesis title: Exploring group 1 metabotropic glutamate receptors in the pathology and treatment of schizophrenia
Muni Mahadari, School of Chemistry and Molecular Bioscience
Supervisor: Senior Professor Stephen Pyne
Thesis title: Development of New Anti-Bacterial Agents
Hiwa Majed, School of Chemistry and Molecular Bioscience
Supervisor: Professor Michael Kelso
Thesis title: Synthesis and Structure-Activity Relationships of New Antibacterials Against Methicillin- Resistant Staphylococcus Aureus and Mycobacterium Tuberculosis
Patrick McCosker, School of Chemistry and Molecular Bioscience
Supervisor: Professor Paul Keller
Thesis title: Cascade Reactions of Indigo: Synthesis and Physicochemical Studies
Mohamed Metwaly, School of Chemistry and Molecular Bioscience
Supervisor: Professor Paul Keller
Thesis title: Drug design and development of antivirals and fluorescent anion transporters
Samuel Millard, School of Medicine
Supervisor: Associate Professor Kelly Newell
Thesis title: The effects of perinatal Fluoxetine treatment on offspring behaviour and neurobiology
Enrico Monachino, School of Chemistry and Molecular Bioscience
Supervisor: Distinguished Professor Antoine van Oijen
Thesis title: Dynamics of the bacterial replisome
Andrew Montgomery, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Danielle Skropeta
Thesis title: Rational Design of Inhibitors Targeting Human Sialyltransferases
Sonia Sanz Munoz, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Lezanne Ooi
Thesis title: Modelling the neurobiology of Alzheimer’s disease in vitro
Ashleigh Osborne, School of Medicine
Supervisor: Doctor Katrina Green
Thesis title: To CBD or Not to CBD? Understanding the Therapeutic Potential of Cannabidiol, a Component of Cannabis, for Schizophrenia
Quynh Thai Son Pham, School of Chemistry and Molecular Bioscience
Supervisor: Professor Stephen Ralph
Thesis title: Synthesis and Quadruplex DNA Binding Properties of Novel Nickel Schiff Base Complexes
Jay Perry, School of Chemistry and Molecular Bioscience
Supervisor: Professor Marie Ranson
Thesis title: Understanding the biology of metastatic cutaneous squamous cell carcinoma
Daniel Rivinoja, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Christopher Hyland
Thesis title: Cycloaddition Reactions with 1,3-Dipoles for the Formation of Complex Heterocycles
Lauren Roach, School of Medicine
Supervisor: Professor Barbara Meyer
Thesis title: The effect of a seaweed sulfated xylorhamnoglucuronan extract on gut, metabolic and skin health outcomes
Greg Ryder, School of Chemistry and Molecular Bioscience
Supervisor: Senior Professor Stephen Pyne
Thesis title: Latent Bis-Nucleophilic Additions to α-Cyclopropyl N-Acyliminium Ions
Sandeep Satapathy, School of Chemistry and Molecular Bioscience
Supervisor: Senior Professor Mark Wilson
Thesis title: Clusterin Enigma: Structure and Function Studies of the First Known Mammalian Secreted Chaperone
Geraud Sansom, School of Chemistry and Molecular Bioscience
Supervisor: Professor Michael Kelso
Thesis title: Anticancer Mutual Prodrugs Activated by Hypoxia
Jo Ann Seng, School of Medicine
Supervisor: Associate Professor Todd Mitchell
Thesis title: Distribution of lipids in the human lens and the effect of ageing
Reece Sophocleous, School of Chemistry and Molecular Bioscience
Supervisor: Professor Ronald Sluyter
Thesis title: Characterisation of canine P2X and P2Y receptors
Sepehr Talebian, School of Chemistry and Molecular Bioscience
Supervisor: Doctor Kara Perrow
Thesis title: Coaxial hydrogel structures for drug delivery to tumors
Srinivas Thadkapally, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Christopher Hyland
Thesis title: Transition Metal Catalyzed [4+2]-Cycloaromatization Reactions of Unconjugated Enediynes
Heema Vyas, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Martina Sanderson-Smith,
Thesis title: Characterising the Role of Pharyngeal Cell Surface Glycans in Group A Streptococcus Biofilm Formation
Samantha Wade, School of Chemistry and Molecular Bioscience
Supervisor: Doctor Kara Perrow
Thesis title: Fabrication and Preclinical Assessment of Drug Eluting Wet Spun Fibres for Pancreatic Cancer Treatment
Jennifer West, School of Chemistry and Molecular Bioscience
Supervisor: Senior Professor Mark Wilson
Student: Thesis title: Extracellular Chaperones and their Cell Surface Receptor
Jonathan Williams, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Martina Sanderson-Smith
Thesis title: Characterising the Neutrophil Response to Group A Streptococcus
Hendris Wongso, School of Chemistry and Molecular Bioscience
Supervisor: Professor Paul Keller
Thesis title: The Development of Novel Fluorescent and Radiopharmaceutical Probes for Imaging Neurodegenerative Diseases
Farzad Zamani, School of Chemistry and Molecular Bioscience
Supervisor: Associate Professor Christopher Hyland
Thesis title: Synthesis and Transition Metal-catalysed Reactivity of Enantioenriched, Allenes and Enynes
Peng Zheng, School of Medicine
Supervisor: Distinguished Professor Xu-Feng Huang
Thesis title: The Mechanism of D2R Overactivation in Neurite Impairment and Oxidative Stress
2019
- Angewandte Chemie – International Edition (2019) 58: 6492-6501
Reshaping Lipid Biochemistry by Pushing Barriers in Structural Lipidomics
Tiffany Porta Siegel; Kim Ekroos; Shane Ellis - Angewandte Chemie – International Edition (2019) 58: 2114-2119
Dual Gold‐Catalyzed Cycloaromatization of Unconjugated (E)‐Enediynes
Farzad Zamani; Rasool Babaahmadi; Brian Yates; Michael Gardiner; Alireza Ariafard; Stephen Pyne; Christopher Hyland - Chemical Science (2019) 10: 8083-8093
The partial dehydrogenation of aluminium dihydrides
Thomas Hooper; Samantha Lau; Wenyi Chen; Ryan Brown; Marti Garcon; Karen Luong; Nathan Barrow; Andrew Tatton; George Sackman; Christopher Richardson
- Chemical Science (2019) 10: 9051-9056
Divergent Pd-catalyzed cross-coupling of allenyloxazolidinones to give chiral 1,3-dienes and vinyloxazolidinones
Ronald Brown; Farzad Zamani; Michael Gardiner; Haibo Yu; Stephen Pyne; Christopher Hyland - Nucleic Acids Research (2019) 47: 2946-2965
RecFOR epistasis group: RecF and RecO have distinct localizations and functions in Escherichia coli
Sarah Henrikus; Camille Henry; Harshad Ghodke; Elizabeth Wood; Neema Mbele; Roopashi Saxena; Upasana Basu; Antoine van Oijen; Michael Cox; Andrew Robinson
- Nucleic Acids Research (2019) 47: 4111-4123
Recycling of single-stranded DNA-binding protein by the bacterial replisome
Lisanne Spenkelink; Jacob Lewis; Slobodan Jergic; Zhi-Qiang Xu; Andrew Robinson; Nicholas Dixon; Antoine van Oijen
2020
- Chemical Science (2020) 11: 10945-10950
Rhodium-catalysed tetradehydro-Diels-Alder reactions of enediynes: Via a rhodium-stabilized cyclic allene
Srinivas Thadkapally; Kaveh Farshadfar; Melanie Drew; Christopher Richardson; Alireza Ariafard; Stephen Pyne; Christopher Hyland
- Molecular Cell (2020) 77: 17-25
Tunability of DNA Polymerase Stability during Eukaryotic DNA Replication
Jacob Lewis; Lisanne Spenkelink; Grant Schauer; Olga Yurieva; Stefan Mueller; Varsha Natarajan; Gurleen Kaur; Claire Maher; Callum Kay; Michael O'Donnell; Antoine van Oijen - Molecular Cell (2020) 79: 140-154
A Primase-Induced Conformational Switch Controls the Stability of the Bacterial Replisome
Enrico Monachino; Slobodan Jergic; Jacob Lewis; Zhi-Qiang Xu; Allen Lo; Valerie O'Shea; James Berger; Nicholas Dixon; Antoine van Oijen - Nature (2020) 579: 141-145
Selective loading and processing of prespacers for precise CRISPR adaptation
Sungchul Kim; Luuk Loeff; Sabina Colombo; Slobodan Jergic; Stan Brouns; Chirlmin Joo
- Nature Communications (2020) 11: 1477
Single-molecule live-cell imaging visualizes parallel pathways of prokaryotic nucleotide excision repair
Harshad Ghodke; Han Ho; Antoine van Oijen - Nature Communications (2020) 11: 1478
Single-molecule imaging reveals molecular coupling between transcription and DNA repair machinery in live cells
Han Ho; Antoine van Oijen; Harshad Ghodke - Nature Communications (2020) 11: 1519
CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation
Yichen Zhong; Bishnu Paudel; Daniel Ryan; Jason Low; Charlotte Franck; Karishma Patel; Max Bedward; Mario Torrado; Richard Payne; Antoine van Oijen; Joel Mackay
Progress in Heterocyclic Chemistry
The Oxford Handbook of the Neurobiology of Pain
Invertebrate Models of Nociception: Learning from Flies and Worms
Daniel Hesselson; Denise Walker; Joshua Massingham; William Schafer; G Neely; Yee Lian Chew
Acta Crystallographica Section E: Crystallographic Communications
Synthesis and crystal structure of (±)-Goniotamirenone C
Pornphimol Meesakul; Christopher Richardson; Surat Laphookhieo; Stephen Pyne
Zhenyu Zhang; Ping Yu; Hui Chang; Sim Lau; Cui Tao; Ning Wang; Mengyang Yin; Chao Deng
American Journal of Physiology - Cell Physiology
Analytical and Bioanalytical Chemistry
Andrew Bowman; Jeroen Bogie; Jerome Hendriks; Mansour Haidar; Mikhail Belov; Ron Heeren; Shane Ellis
Stefan Mueller; Lisanne Spenkelink; Antonius van Oijen; Jacob Lewis
Andrew Bowman; Greg Blakney; Christopher Hendrickson; Shane Ellis; Ron Heeren; Donald Smith
Simultaneous Detection of Zinc and Its Pathway Metabolites Using MALDI MS Imaging of Prostate Tissue
Angewandte Chemie - International Edition
Angewandte Chemie - International Edition
Stimuli-Responsive Cycloaurated “OFF-ON” Switchable Anion Transporters
Association of a P2RX7 gene missense variant with brachycephalic dog breeds
Overeating and food addiction in Major Depressive Disorder: Links to peripheral dopamine
Jessica Mills; Susan Thomas; Theresa Larkin; Chao Deng
Bipolar electroactive conducting polymers for wireless cell stimulation
Australian Journal of Chemistry
Markus Muttenthaler; Simon Nevin; Marco Inserra; Richard Lewis; David Adams; Paul Alewood
Australian Journal of Chemistry
Barrierless Reactions of Three Benzonitrile Radical Cations with Ethylene
Oisin Shiels; Patrick Kelly; Stephen Blanksby; Gabriel da Silva; Adam Trevitt
Behavioral Ecology and Sociobiology
Covariation in superoxide, sperm telomere length and sperm velocity in a polymorphic reptile
Christopher Friesen; Nicky Rollings; Mark Wilson; Camilla Whittington; Richard Shine; Mats Olsson
Ari Nugraha; Bawon Triatmoko; Phurpa Wangchuk; Paul Keller
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry
Design, synthesis and evaluation of carbamate-linked uridyl-based inhibitors of human ST6Gal I
BMC Pharmacology and Toxicology
Brown adipose tissue activity is modulated in olanzapine-treated young rats by simvastatin
Xuemei Liu; Xiyu Feng; Chao Deng; Lu Liu; Yanping Zeng; Chang Hu
Differential susceptibility of human neural progenitors and neurons to ischaemic injury
Ye Liu; Anna Michalska; Mirella Dottori; Emma Eaton; Jo Courtney; Ana Antonic; David Howells
Insights into the role of sialylation in cancer progression and metastasis
Christopher Dobie; Danielle Skropeta
British Journal of Pharmacology
British Journal of Pharmacology
Pharmacological and genetic characterisation of the canine P2X4 receptor
Chemical Biology and Drug Design
Linear triazole-linked pseudo oligogalactosides as scaffolds for galectin inhibitor development
Second-order programming the synthesis of metal-organic frameworks
Mitchell Fishburn; Dayne Skelton; Shane Telfer; Pawel Wagner; Christopher Richardson
Mixed donor, phenanthroline photoactive MOFs with favourable CO<inf>2</inf>selectivity
Huong Ta; A Tieu; Hongtao Zhu; Haibo Yu; Nam Tran; Bach Tran; Shanhong Wan; Thi Ta
Surface transformation and interactions of iron oxide in glassy lubricant: An ab initio study
Manh Ha Le; Anh Tieu; Hongtao Zhu; Thi Ta; Haibo Yu; Thi Thuy Huong Ta; V Tran
CNS Neuroscience and Therapeutics
Xiao Wan; Fan Zeng; Xu-Feng Huang; He-Qin Yang; Lan Wang; Yan-Chuan Shi; Zhi-Hui Zhang; Shu Lin
Timothy Ablott; Shane Telfer; Christopher Richardson
Xiangjia Zhu; Yu Du; Roger Truscott; Wenwen He; Peng Zhou; Yi Lu
Vinicius do rosario; Jaclyn Spencer; Katrina Green; Karen Charlton
Current Opinion in Structural Biology
Polarisable force fields: what do they add in biomolecular simulations?
V Inakollu; Daan Geerke; Christopher Rowley; Haibo Yu
A new class of quadruplex DNA-binding nickel Schiff base complexes
Macguire Bryant; Christopher Richardson
Dalton Transactions: an international journal of inorganic chemistry
Son Pham; Christopher Richardson; Celine Kelso; Anthony Willis; Stephen Ralph
Fereshteh Azamifar; M Naimi-Jamal; Ardeshir Rineh; Michael Kelso
Approaches to learning: Does medical school attract students with the motivation to go deeper?
Kylie Mansfield; Gregory Peoples; Lyndal Parker-Newlyn; Danielle Skropeta
More than a Corepressor: The Role of CoREST Proteins in Neurodevelopment
Simon Maksour; Lezanne Ooi; Mirella Dottori
Vinicius do Rosario; Danielle Schoenaker; Katherine Kent; Katrina Green; Karen Charlton
European Journal of Pharmaceutics and Biopharmaceutics
Nikolas Johnston; James Wallman; Mark Dowton; Krzysztof Szpila; Thomas Pape
Frontiers in Cellular Neuroscience
Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises
Luke McAlary; Yee Lian Chew; Jeremy Lum; Nicholas Geraghty; Justin Yerbury; Neil Cashman
Antibiotic-Induced Mutagenesis: Under the Microscope
Sarah Revitt-Mills; Andrew Robinson
Curdlan Prevents the Cognitive Deficits Induced by a High-Fat Diet in Mice via the Gut-Brain Axis
Prevention of Neurite Spine Loss Induced by Dopamine D2 Receptor Overactivation in Striatal Neurons
Peng Zheng; Qian Su; Dayong Jin; Yinghua Yu; Xu-Feng Huang
Latitudinal biogeographic structuring in the globally distributed moss Ceratodon purpureus
The Role of Cathepsins in Memory Functions and the Pathophysiology of Psychiatric Disorders
Christine Niemeyer; Natalie Matosin; Dominic Kaul; Alexandra Philipsen; Nils Gassen
Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface
Fabian Kreilaus; Stefan Guerra; Rebecca Masanetz; Victoria Menne; Justin Yerbury; Tim Karl
The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins
An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides
Sam Adhikary; Peter Cuthbertson; Ross Turner; Ronald Sluyter; Debbie Watson
International Journal for Parasitology
International Journal of Mass Spectrometry
Protonation isomers of highly charged protein ions can be separated in FAIMS-MS
International Journal of Molecular Sciences
Reece Sophocleous; Nicole Miles; Lezanne Ooi; Ronald Sluyter
Iranian Journal of Basic Medical Sciences
Phuong Mai; Quang van Ngo; Minh Hong; Lien Quach; Stephen Pyne
Iranian Journal of Pharmaceutical Research
Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS
Journal of Antimicrobial Chemotherapy
Non-zero spontaneous magnetic moment along crystalline b-axis for rare earth orthoferrites
Mohanad Mohammed; Z Cheng; Shixun Cao; K Rule; C Richardson; A Edwards; A Studer; J Horvat
Journal of Biological Chemistry
Emily Selig; Courtney Zlatic; Dezerae Cox; Yee-Foong Mok; Paul Gooley; Heath Ecroyd; Michael Griffin
Journal of Biological Inorganic Chemistry
Dale Ang; Celine Kelso; Jennifer Beck; Stephen Ralph; David Harman; Janice Aldrich-Wright
Journal of Biomolecular Structure and Dynamics
Nathan Butterworth; Falko Drijfhout; Phillip Byrne; Paul Keller; James Wallman
Journal of Clinical Endocrinology and Metabolism
Maternal adipose tissue expansion, a missing link in the prediction of birth weight centile
Journal of Computational Chemistry
Thomas Griffiths; Aaron Oakley; Haibo Yu
Journal of Evolutionary Biology
The evolution of sexually dimorphic cuticular hydrocarbons in blowflies (Diptera: Calliphoridae)
Nathan Butterworth; James Wallman; Falko Drijfhout; Nikolas Johnston; Paul Keller; Phillip Byrne
Journal of Materials Chemistry B
Journal of Materials Chemistry B
Coaxial mussel-inspired biofibers: Making of a robust and efficacious depot for cancer drug delivery
Sepehr Talebian; In Shim; Song Kim; Geoffrey Spinks; Kara Vine; Javad Foroughi
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry
Jiazhen Liang; Han-Shen Tae; Xiaoxiao Xu; Tao Jiang; David Adams; Rilei Yu
Journal of Medicinal Chemistry
Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors
Journal of Medicinal Chemistry
Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors
Journal of Medicinal Chemistry
Journal of Photochemistry and Photobiology B: Biology
Chaki Borras; Ronald Sluyter; Philip Barker; Konstantin Konstantinov; Shahnaz Bakand
Journal of Physical Organic Chemistry
Predicting phosphirane air stability using density functional theory
Jayden Gaston; Patrick McCosker; Haibo Yu; Paul Keller
Journal of Psychiatric Research
Journal of Psychiatric Research
Safety and Efficacy of Using Nuts to Improve Bowel Health in Hemodialysis Patients
Journal of the American Chemical Society
DHA reduces hypothalamic inflammation and improves central leptin signaling in mice
Licai Cheng; Tao Hu; Hongli Shi; Xi Chen; Hongqin Wang; Kuiyang Zheng; Xu-Feng Huang; Yinghua Yu
Jierong Wen; David Adams; Andrew Hung
β-glucan attenuates cognitive impairment via the gut-brain axis in diet-induced obese mice
Tunability of DNA Polymerase Stability during Eukaryotic DNA Replication
A Primase-Induced Conformational Switch Controls the Stability of the Bacterial Replisome
D Vos; S Ellis; B Balluff; R Heeren
Sirinrat Chalom; Jukreera Panyakaew; Manlika Phaya; Stephen Pyne; Pitchaya Mungkornasawakul
Phuong Nguyen; Quang Ngo; Minh Hue Nguyen; Alan Maccarone; Stephen Pyne
Selective loading and processing of prespacers for precise CRISPR adaptation
Sungchul Kim; Luuk Loeff; Sabina Colombo; Slobodan Jergic; Stan Brouns; Chirlmin Joo
Han Ho; Antonius van Oijen; Harshad Ghodke
Harshad Ghodke; Han Ho; Antonius van Oijen
CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation
Alexander Harper; Katrina Rimmer; Jhansi Dyavanapalli; Jeffrey McArthur; David Adams
If Human Brain Organoids Are the Answer to Understanding Dementia, What Are the Questions?
Development of a single-stranded DNA-binding protein fluorescent fusion toolbox
Cassandra Sparkes; Andrew Sinclair; Robert Gibson; Paul Else; Barbara Meyer
Inge van der Wurff; Barbara Meyer; Renate de Groot
Setyaningrum Rahmawaty; Barbara Meyer
Organic and Biomolecular Chemistry
Five-membered cyclic sulfamidate imines: versatile scaffolds for organic synthesis
Quoc Hoang Pham; Christopher Hyland; Stephen Pyne
N-alkylisatin-loaded liposomes target the urokinase plasminogen activator system in breast cancer
Lisa Belfiore; Darren Saunders; Marie Ranson; Kara Perrow
Yueqing Su; Xuemei Liu; Jiamei Lian; Chao Deng
Pharmacology Biochemistry and Behavior
Pharmacology Biochemistry and Behavior
Emma Sylvester; Weijie Yi; Mei Han; Chao Deng
Physical Chemistry Chemical Physics
Sui So; Benjamin Kirk; Uta Wille; Adam Trevitt; Stephen Blanksby; Gabriel da Silva
Physical Chemistry Chemical Physics
Styryllactones from Goniothalamus tamirensis
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Samuel Millard; Katrina Weston-Green; Kelly Newell
Prostaglandins Leukotrienes and Essential Fatty Acids
Renate de Groot; Barbara Meyer
Shengyun Chen; Xiaowei Xia; Chao Deng; Xiuhua Wu; Zili Han; Jiong Tao; Xiaoli Wu
Rapid Communications in Mass Spectrometry
Mats Olsson; Nicholas Geraghty; Erik Wapstra; Mark Wilson
Sandeep Satapathy; Rebecca Dabbs; Mark Wilson
N-acetylcysteine prevents olanzapine-induced oxidative stress in mHypoA-59 hypothalamic neurons
Zehra Boz; Minmin Hu; Yinghua Yu; Xu-Feng Huang
Yongmin Cho; Sol Lee; Yee Chew; Kirby Broderick; William Schafer; Hang Lu
Melissa Bird; Steven Wales; Christopher Richardson; Christopher Hyland
Synthesis of thioridazine-VLA-4 antagonist hybrids using N-propargyl northioridazine enantiomers
Alexander Martyn; Anthony Willis; Michael Kelso
Intramolecular interception of the Newman-Kwart rearrangement by carboxylic acids
Timothy Ablott; Mitchell Fishburn; David Turner; Christopher Richardson
Early and mid-career scientists face a bleak future in the wake of the pandemic
Assessing the role of pharyngeal cell surface glycans in group a streptococcus biofilm formation
The Journal of experimental medicine
Peng Gao; Zhenguo Huang; Haibo Yu
The journal of physical chemistry letters
Samuel Marlton; Benjamin McKinnon; Boris Ucur; James Bezzina; Stephen Blanksby; Adam Trevitt
Geoff Zhang; Min Hu; Debbie Watson; Yuan Min Wang; John Knight; Stephen Alexander
Proteome Homeostasis Dysfunction: A Unifying Principle in ALS Pathogenesis
Justin Yerbury; Natalie Farrawell; Luke McAlary
Encyclopedia of Gerontology and Population Aging
Recent Advances in Cannabinoid Research
ACS Applied Materials and Interfaces
Haoran Guo; Lei Li; Xingyong Wang; Ge Yao; Haibo Yu; Ziqi Tian; Baihai Li; Liang Chen
Natalie Farrawell; Maddison Yerbury; Steven Plotkin; Luke McAlary; Justin Yerbury
Xin Chu; Han-Shen Tae; Qingliang Xu; Tao Jiang; David Adams; Rilei Yu
Peng Gao; Xingyong Wang; Zhenguo Huang; Haibo Yu
Acta Neuropathologica Communications
Xue-mei Liu; Xiao-min Zhao; Chao Deng; Yan-ping Zeng; Chang-Hua Hu
Advanced Theory and Simulations
Peng Gao; Xingyong Wang; Haibo Yu
Rapid Identification of Ischemic Injury in Renal Tissue by Mass-Spectrometry Imaging
Angewandte Chemie - International Edition
Reshaping Lipid Biochemistry by Pushing Barriers in Structural Lipidomics
Tiffany Porta Siegel; Kim Ekroos; Shane Ellis
Angewandte Chemie International Edition
Dual Gold‐Catalyzed Cycloaromatization of Unconjugated (E)‐Enediynes
Carbapenem sparing in the management of post-transrectal prostate biopsy bacteraemia
Asia-Pacific Journal of Clinical Oncology
High tolerance of repeated heatwaves in Australian native plants
Kris French; Isaac Jansens; Michael Ashcroft; Heath Ecroyd; Sharon Robinson
Australian Journal of Chemistry: an international journal for chemical science
The Elusive Nitro-Functionalised Member of the IRMOF-9 Family
Cleavage C-terminal to Asp leads to covalent crosslinking of long-lived human proteins
Zhen Wang; Michael Friedrich; Roger Truscott; Kevin Schey
Mechanism of protein cleavage at asparagine leading to protein-protein cross-links
Michael Friedrich; Zhen Wang; Kevin Schey; Roger Truscott
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters
Identification of Multiple Kinetic Populations of DNA-Binding Proteins in Live Cells
Han Ho; Daniel Zalami; Jurgen Kohler; Antonius van Oijen; Harshad Ghodke
When proteins play tag: the dynamic nature of the replisome
Stefan Mueller; Lisanne Spenkelink; Antoine van Oijen
Helen Macpherson; Sarah Brownell; Rachel Duckham; Barbara Meyer; Sam Mirzaee; Robin Daly
Renate de Groot; Rebecca Emmett; Barbara Meyer
British Journal of Pharmacology
Jeffrey McArthur; Rocio Finol-Urdaneta; David Adams
British Journal of Pharmacology
Rilei Yu; Han-Shen Tae; Qingliang Xu; David Craik; David Adams; Tao Jiang; Quentin Kaas
Catalysis Science and Technology
Maryam Asgari; Christopher Hyland; A. Stephen Hashmi; Brian Yates; Alireza Ariafard
Small heat shock proteins: multifaceted proteins with important implications for life
N Geraghty; D Watson; R Sluyter
Highly diastereoselective synthesis of enantioenriched anti-α-allyl-β-fluoroamines
Divergent gold-catalysed reactions of cyclopropenylmethyl sulfonamides with tethered heteroaromatics
The partial dehydrogenation of aluminium dihydrides
Ronald Brown; Farzad Zamani; Michael Gardiner; Haibo Yu; Stephen Pyne; Christopher Hyland
Chemistry and Physics of Lipids
Reaction of ionised steryl esters with ozone in the gas phase
Sarah Hancock; Alan Maccarone; Berwyck Poad; Adam Trevitt; Todd Mitchell; Stephen Blanksby
Lennart Huizing; Shane Ellis; Bart Beulen; Florian Barré; Paul Kwant; Rob Vreeken; Ron Heeren
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Qiming Hu; Jie Yang; Khin Win; Xufeng Huang
Critical Reviews in Toxicology
Afsaneh Khansari; Shane Telfer; Christopher Richardson
Macguire Bryant; Timothy Ablott; Shane Telfer; Lujia Liu; Christopher Richardson
Interpenetration isomers in isoreticular amine-tagged zinc MOFs
Benjamin Buckley; Umar Ali; Michael Kelso; Marie Ranson
Current understanding of Group A Streptococcal biofilms
Heema Vyas; Emma-Jayne Proctor; Jason McArthur; Jody Gorman; Martina Sanderson-Smith
Current Opinion in Biomedical Engineering
Spy-ing on Cas9: Single-molecule tools reveal the enzymology of Cas9
Kelsey Whinn; Antoine van Oijen; Harshad Ghodke
Ecotoxicology and Environmental Safety
Spatial and temporal organization of RecA in the Escherichia coli DNA-damage response
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry
A tocotrienol quinone dimer and xanthones from the leaf extract of Garcinia nigrolineata
Achara Raksat; Wisanu Maneerat; Raymond Andersen; Stephen Pyne; Surat Laphookhieo
Frontiers In Cell And Developmental Biology
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Nicholas Geraghty; Debbie Watson; Ronald Sluyter
Alexandra Anderson; Yee Chew; William Schafer; Rachel McMullan
Dynamic solution behaviour of metal complexes of the hexaamine cage ligand Me8tricosane
Leighton Alcock; German Cavigliasso; Douglas Lawes; Robert Stranger; James Hook; Stephen Ralph
International Immunopharmacology
N Geraghty; S Adhikary; D Watson; R Sluyter
International Journal of Cancer
International Journal of Mass Spectrometry
International Journal of Mass Spectrometry
Class-specific depletion of lipid ion signals in tissues upon formalin fixation
D Vos; Andrew Bowman; Ron Heeren; Benjamin Balluff; Shane Ellis
Investigative Ophthalmology and Visual Science
Molecular Processes Implicated in Human Age-Related Nuclear Cataract
Roger Truscott; Michael Friedrich
Journal of Autism and Developmental Disorders
Activated carbon preparation from biomass feedstock: Clean production and carbon dioxide adsorption
Journal of Computational Chemistry
Quantum Chemical Methods for Modeling Covalent Modification of Biological Thiols
Journal of Investigative Dermatology
Mutational Patterns in Metastatic Cutaneous Squamous Cell Carcinoma
Sarah Hancock; Berwyck Poad; Mark Willcox; Stephen Blanksby; Todd Mitchell
Polyoxygenated Cyclohexenes and Their Chlorinated Derivatives from the Leaves of Uvaria cherrevensis
Corrected Structure of Natural Hyacinthacine C <inf>1</inf> via Total Synthesis
Anthony Carroll; Anthony Willis; Masako Hoshino; Atsushi Kato; Stephen Pyne
Amides and Flavonoids from the Fruit and Leaf Extracts of Melodorum siamensis
Pornphimol Meesakul; Christopher Richardson; Stephen Pyne; Surat Laphookhieo
Mallopenins A-E, Antibacterial Phenolic Derivatives from the Fruits of Mallotus philippensis
Sarot Cheenpracha; Stephen Pyne; Brian Patrick; Raymond Andersen; Wisanu Maneerat; Surat Laphookhieo
Dasymaschalolactams A-E, Aristolactams from a Twig Extract of Dasymaschalon dasymaschalum
Journal of Neuropathology and Experimental Neurology
Claire Stevens; Natalie Guthrie; Marloes van Roijen; Glenda Halliday; Lezanne Ooi
Journal of Nutritional Biochemistry
Nicholas Butler; John Bremner; Anthony Willis; Leonardo Lucantoni; Vicky Avery; Paul Keller
Journal of Physical Chemistry B
Mechanisms of Pressure-Induced Structural Transformation in Confined Sodium Borate Glasses
Thi Thuy Huong Ta; Anh Tieu; Hongtao Zhu; Haibo Yu; Nam Van Tran; Thi Ta
Strategies for managing multi-patient 3D mass spectrometry imaging data
Samuel Millard; Jeremy Lum; Francesca Fernandez; Katrina Weston-Green; Kelly Newell
Journal of the American Society for Mass Spectrometry
Julian Harrison; Celine Kelso; Tara Pukala; Jennifer Beck
Journal of the American Society for Mass Spectrometry
Mapping Unsaturation in Human Plasma Lipids by Data-Independent Ozone-Induced Dissociation
Journal of the American Society for Mass Spectrometry
Combining Charge-Switch Derivatization with Ozone-Induced Dissociation for Fatty Acid Analysis
Malaysian Journal of Nutrition
Sensitivity of plasma cholecystokinin and peptide YY in obese and normal weight men
Dian Handayani; Inggita Kusumastuty; Sri Andarini; Nindy Sabrina; Achmad Rudijanto; Xu-Feng Huang
Effects of antipsychotic drugs on neurites relevant to schizophrenia treatment
Generation of Neural Crest Progenitors from Human Pluripotent Stem Cells
Kwaku Dad Abu-Bonsrah; Serena Viventi; Donald Newgreen; Mirella Dottori
Monoclonal antibody-conjugated dendritic nanostructures for siRNA delivery
Hitesh Kulhari; Ashok Jangid; David Adams
Microbes and Infection: a journal on infectious agents and host defenses
Microfluidics and Nanofluidics
Dean-flow-coupled elasto-inertial particle and cell focusing in symmetric serpentine microchannels
Molecular Phylogenetics and Evolution
Drivers of sociality in Gobiodon fishes: An assessment of phylogeny, ecology and life-history
Martin Hing; O Klanten; Marian Wong; Mark Dowton
Shining a spotlight on DNA: Single-molecule methods to visualise DNA
Gurleen Kaur; Jacob Lewis; Antoine van Oijen
Gholamhossein Khalili; Patrick McCosker; Timothy Clark; Paul Keller
Ari Nugraha; Yuvita Damayanti; Phurpa Wangchuk; Paul Keller
Natural Product Communications: an international journal for communications and reviews
Nilawan Surapong; Aphidech Sangdee; Kittipong Chainok; Stephen Pyne; Prapairat Seephonkai
Natural Product Communications: an international journal for communications and reviews
Ari Nugraha; Tashi Wangchuk; Anthony Willis; Rachada Haritakun; Heri Sujadmiko; Paul Keller
Sarot Cheenpracha; Pannakorn Boapun; Thunwadee Limtharakul; Surat Laphookhieo; Stephen Pyne
Alkaloids from the root of Indonesian Annona muricata L
Ari Nugraha; Rachada Haritakun; Jacob Lambert; Carolyn Dillon; Paul Keller
A new xanthone and a biphenyl from the flower and twig extracts of Garcinia mckeaniana
Comparative genetic architectures of schizophrenia in East Asian and European populations
Understanding the Role of ApoE Fragments in Alzheimer’s Disease
Sonia Sanz Munoz; Brett Garner; Lezanne Ooi
Justin Yerbury; Lezanne Ooi; Ian Blair; Prajwal Ciryam; Christopher Dobson; Michele Vendruscolo
Alexander Harris; Patrick McGivern; Lezanne Ooi
RecFOR epistasis group: RecF and RecO have distinct localizations and functions in Escherichia coli
Recycling of single-stranded DNA-binding protein by the bacterial replisome
Organic and Biomolecular Chemistry
Greg Ryder; Uta Wille; Anthony Willis; Stephen Pyne
Curtis Ho; Alireza Ariafard; Christopher Hyland; Alex Bissember
Oxidative Medicine And Cellular Longevity
Alpha-2-Macroglobulin, a Hypochlorite-Regulated Chaperone and Immune System Modulator
Jordan Cater; Mark Wilson; Amy Wyatt
Expression of cancer stem cell markers is prognostic in metastatic gastroesophageal adenocarcinoma
Antidiarrheal activity of some selected Nigerian plants used in traditional medicine
Christiana Dawurung; Jurbe Gotep; Joy Usman; Ishaku Elisha; Lami Lombin; Stephen Pyne
Physical Chemistry Chemical Physics
Alkaloids and styryllactones from Goniothalamus cheliensis
Proceedings of the National Academy of Sciences of the United States of America
Proceedings Of The National Academy Of Sciences Of The United States Of America
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Peng Zheng; Minmin Hu; Yuanyi Xie; Yinghua Yu; Hanna Jaaro-Peled; Xu-Feng Huang
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Progress in Neuropsychopharmacology and Biological Psychiatry
Carlos Jimenez Naranjo; Ashleigh Osborne; Katrina Weston-Green
A structural view of bacterial DNA replication
Early antipsychotic exposure affects NMDA and GABAA receptor binding in the brains of juvenile rats
Jessica Mills; Theresa Larkin; Chao Deng; Susan Thomas
Meng He; Xu-Feng Huang; Guanbin Gao; Ting Zhou; Wenting Li; Jinqi Hu; Jia Chen; Jing Li; Taolei Sun
S Adhikary; N Geraghty; P Cuthbertson; R Sluyter; D Watson
RSC Advances: an international journal to further the chemical sciences
Enad Abed Mahmood Alabed; Martin Engel; Yusuke Yamauchi; Md Shahriar Hossain; Lezanne Ooi
Secondary nucleation and elongation occur at different sites on Alzheimer's amyloid-b aggregates
Kela Xiao; Xingyong Wang; Haibo Yu
Nuclease dead Cas9 is a programmable roadblock for DNA replication
Alison Scott; Courtney Chandler; Shane Ellis; Ron Heeren; Robert Ernst
Three-Dimensional Mass Spectrometry Imaging Identifies Lipid Markers of Medulloblastoma Metastasis
Lei Li; Xingyong Wang; Haoran Guo; Ge Yao; Haibo Yu; Ziqi Tian; Baihai Li; Liang Chen
PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia
Tomoko Hyakumura; Stuart McDougall; Sue Finch; Karina Needham; Mirella Dottori; Bryony Nayagam
Thanaphat Thaima; Anthony Willis; Stephen Pyne
Human glycan expression patterns influence Group A streptococcal colonization of epithelial cells
The International Journal of Biochemistry and Cell Biology
Bombesin receptors as potential targets for anticancer drug delivery and imaging
Deep Pooja; Anusha Gunukula; Nitin Gupta; David Adams; Hitesh Kulhari
The Journal Of Experimental Biology
Honey bee caste lipidomics in relation to life-history stage and the long life of the queen
Nicolas Martin; A Hulbert; Greg Brenner; Simon Brown; Todd Mitchell; Paul Else
Molecular weight growth in the gas phase reactions of dehydroanilinium radical cations with propene
Patrick Kelly; Cameron Bright; Stephen Blanksby; Gabriel da Silva; Adam Trevitt
The Journal of Steroid Biochemistry and Molecular Biology
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Trends in Analytical Chemistry
Andrew Bowman; Ron Heeren; Shane Ellis
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