Select the microscope best suited to your application
Use the interactive decision tree diagram to quickly locate details of the most appropriate microscope.
Download interactive decision tree diagram (PDF)
Use the interactive decision tree diagram to quickly locate details of the most appropriate microscope.
Download interactive decision tree diagram (PDF)
Features:
Software:
Common Applications:
Features:
Common Applications:
Features:
Software:
Common Applications:
Features:
Software:
Common Applications:
Features:
Software:
Common Applications:
Features:
Light Sources and Filters:
Objectives:
Software
Overview:
Total Internal Reflection Fluorescence (TIRF) is a microscopy technique for the visualization of fluorophores that are immediately adjacent (<250 nm) to a glass coverslip. TIRF microscopes direct the excitation laser at an oblique angle to create total internal reflection that generates a highly restricted electromagnetic field (or evanescent waver) within the specimen.
Common Applications:
Features:
Light Sources and Filters:
Objectives:
Software:
Overview:
Confocal laser scanning microscopy is one of the most popular techniques for imaging fluorophores in biological specimens. This optical imaging method increases optical resolution, contrast and in-focused images by removing out of focus light during image collection. This is achieved by using a spatial pinhole. Confocal specimens are illuminated by a focused point of laser light that is scanned across the specimen in the horizontal plane. Capturing multiple 2D images at different depths enables the reconstruction of 3D structures within a sample.
Common Applications:
Features:
Light Sources and Filters:
Objectives:
Software and modules available:
Overview:
SP8 FALCON (FAst Lifetime CONtrast) a powerful microscope equipped with a truly integrated solution for Fluorescence Lifetime Imaging (FLIM), Fluorescence Resonance Energy Transfer (FRET) and Fluorescence Correlation Spectroscopy (FCS) to investigate cellular physiology and explore dynamics in living cells.
Common Applications:
Features:
Light Sources and Filters:
Objectives:
Software:
Applications:
The Reversible Saturable Optical Fluorescence Transitions (RESOLFT) superresolution microscopy
RESOLFT stands for a general switching principle: the switching mechanism does no longer need to be purely electronically but can include switching mechanisms like for example conformational changes of a molecule. Strictly speaking, the STED method is one possible implementation of the RESOLFT concept. The approach is similar as shown for STED – a beam scanning setup with overlapping beams of the excitation and the switching beam.
Features:
High precision, compact micromanipulator system to simplify intracellular injection. It is capable of delivering precise nanoliter volumes of diverse compounds and biomolecules.
Features:
Objectives: