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Equipment
Waters Synapt™ HDMS
Type: Quadrupole (TWIMS) Time-of-flight
Comments: Triwave technology with high efficiency ion mobility spectrometry enabling sample separation based on their mass as well as their size, shape and charge
Sources: Electrospray (ESI), nanospray and lockspray
Use: Ion mobility study, time aligned parallel fragmentation for structural analysis, high mass protein and DNA research and accurate mass analysis

Waters Qtof Ultima
- Type: Quadrupole Time-of-flight
- Comments: Factory modified for high mass/charge transmission
- Sources: Electrospray (ESI), nanospray, lockspray
- Use: High mass protein and DNA research. Accurate mass analysis.

Waters Quattro Micro
- Type: Triple Quadrupole
- Sources: Electrospray (ESI), nanoflow
- Use: Gas phase radical reactions, and lipid research

Waters Platform LCZ
- Type: Single quadrupole
- Sources: Electrospray (ESI)
- Use: Compound structure.

Thermo Finnigan LTQ
- Type: Linear Ion Trap, with tandem LC and autosampler
- Sources: Electrospray (ESI), nanoflow, desorption electrospray (DESI)
- Use: Gas phase radical reactions, and lipid research

Shimadzu QP5050
- Type: Gas chromatoraphy / single quadrupole
- Sources: Electron impact (EI), chemical ionization (CI), and solids probe.
- Use: Purity testing, compound structure.

Waters Xevo
- Type: Quadrupole Time-of-flight
- Sources: Electrospray (ESI), Lockspray and Atmospheric Solids Analysis Probe (ASAP)
- Use: Accurate mass analysis, high resolution mass spectrometry, tandem mass spectrometry.
- Additional Features: UPLC-MS and GC-MS.

AB SCIEX Q-Trap 2000
- Type: Triple quadrupole and linear ion trap
- Sources: Electrospray
- Uses: This instrument is part of a collaboration with AB Sciex (Toronto, Canada) and has been modified to measure Ozone Induced Dissociation (OzID) mass spectra. OzID was invented in our lab and uses a selective reaction between the ion and ozone gas to cleave double bonds and reveal their position(s) within the molecular. OzID is used routinely for structural characterisation of lipids.

AB SCIEX Q-Trap 5500
- Type: Triple quadrupole and linear ion trap
- Sources: Electrospray, Advion Nanomate (chip-based nanoESI)
- Uses: The instrument is part of the UoW lipidomics facility and is used for the identificaiton and quantification of a wide range of lipids in extracts from diverse sources including, human lens tissue, tears, contact lens and cell culture. The automated nanomate source allows the investigation of large sample arrays.

Last reviewed: 3 November, 2011





