Equipment

Waters Synapt™ HDMS

Type: Quadrupole (TWIMS) Time-of-flight

Comments: Triwave technology with high efficiency ion mobility spectrometry enabling sample separation based on their mass as well as their size, shape and charge

Sources: Electrospray (ESI), nanospray and lockspray

Use: Ion mobility study, time aligned parallel fragmentation for structural analysis, high mass protein and DNA research and accurate mass analysis

                   

 Waters Qtof Ultima

• Type: Quadrupole Time-of-flight
• Comments: Factory modified for high mass/charge transmission
• Sources: Electrospray (ESI), nanospray, lockspray
• Use: High mass protein and DNA research.  Accurate mass analysis.

 

 Waters Quattro Micro

• Type: Triple Quadrupole
• Sources: Electrospray (ESI), nanoflow
• Use: Gas phase radical reactions, and lipid research

 

 Waters Platform LCZ

• Type: Single quadrupole
• Sources: Electrospray (ESI)
• Use: Compound structure.

 

 Thermo Finnigan LTQ

• Type: Linear Ion Trap, with tandem LC and autosampler
• Sources: Electrospray (ESI), nanoflow, desorption electrospray (DESI)
• Use: Gas phase radical reactions, and lipid research

 

 

 Shimadzu QP5050

• Type: Gas chromatoraphy / single quadrupole
• Sources: Electron impact (EI), chemical ionization (CI), and solids probe.
• Use: Purity testing, compound structure.

Waters Xevo

• Type: Quadrupole Time-of-flight
• Sources: Electrospray (ESI), Lockspray and Atmospheric Solids Analysis Probe (ASAP)
• Use: Accurate mass analysis, high resolution mass spectrometry, tandem mass spectrometry.
• Additional Features:  UPLC-MS and GC-MS.

 

AB SCIEX Q-Trap 2000

• Type: Triple quadrupole and linear ion trap
• Sources: Electrospray
• Uses:  This instrument is part of a collaboration with AB Sciex (Toronto, Canada) and has been modified to measure Ozone Induced Dissociation (OzID) mass spectra.  OzID was invented in our lab and uses a selective reaction between the ion and ozone gas to cleave double bonds and reveal their position(s) within the molecular.  OzID is used routinely for structural characterisation of lipids.

 

AB SCIEX Q-Trap 5500

• Type: Triple quadrupole and linear ion trap
• Sources: Electrospray, Advion Nanomate (chip-based nanoESI)
• Uses:  The instrument is part of the UoW lipidomics facility and is used for the identificaiton and quantification of a wide range of lipids in extracts from diverse sources including, human lens tissue, tears, contact lens and cell culture.  The automated nanomate source allows the investigation of large sample arrays.