Biomolecular Mass Spectrometry Lab

Introduction

The Biomolecular Mass Spectrometry Laboratory (BMSL) is a part of the Centre for Biomolecular Science and  Centre for Medicinal  Chemistry and Pharmacology. BMSL includes research groups led by Dr Jennifer Beck and Dr Stephen Blanksby, studying diverse topics such as apoptosis (programmed cell death), the mechanism of cataract formation, proteins invovled in the HIV entry complex, degradation mechanisms in polymer coatings, observation of lipids in cell membranes, fundemental investigations of radicals in the gas phase, and interactions between DNA, drugs and metals.

Mass Spectrometry Group, 2006

Equipment

• Micromass Qtof Ultima with electrospray, nanospray and lockspray ionization sources, and factory modified for high mass charge transmission.
• Micromass Quattro Micro triple quadrupole mass spectrometer with electrospray ionization and nanoflow options
• VG Autospec-oa-tof tandem high resolution mass spectrometer with EI/CI and electrospray ionization
• Micromass LCZ single quadrupole LC/MS
• ThermoFinnigan LTQ Linear Ion Trap mass spectrometer.
• Shimadzu QP5050 GC/MS with solids probe and EI/CI options.
• Range of Beckman and Waters HPLC and capillary LC systems, with capabilities for online LC/MS.

Location

The Biomolecular Mass Spectrometry Laboratory and Facilities are housed in the School of Chemistry, Building 18, Rooms 101, 105, 106 and 113.