John Bremner

Position:  Emeritus Professor

Room:  18.120

Phone No:  +61 2 4221 4255

Email:  john_bremner@uow.edu.au

Research Interests

My research activities are based on the three interacting themes of medicinal chemistry, synthetic heterocyclic chemistry and natural products chemistry.  The main long term goal is centred on the development of new selective medicinal agents for the treatment of diseases.

Representative Publications

Wangchuk, P., Bremner, J.B., Samten, Skelton, B.W., White, A.H., Rattanajack, R. and Kamchonwongpaisan, 'Antiplasmodial Activity of Atisinium Chloride from the Bhutanese Medicinal Plant, Aconitum orochryseum', J. Ethnopharm., 2010, 130, 559-562.

Robertson, M., Bremner, J.B., Coates, J., Deadman, J., Keller, P.A., Pyne, S.G., Somphol, K.  and Rhodes, D.I., 'Synthesis and Antibacterial Activity of C2- Symmetric Binaphthyl Scaffolded Amino Acid Derivaties', Eur. J. Med. Chem., 2011, 46, 4201-4211.

Mbere, J., Bremner, J.B., Skelton, B.W. and White, A.H.  'Synthesis of New Benzo[b]thieno Fused Ring Systems via Transition Metal-Mediated Cyclisations', Tetrahedron, 2011, 67, 6806-6900.

Vine, K.L., Indira Chandran, V., Locke, J.L., Matesic, L., Lee, J., Skropeta, D., Bremner, J.B., and Ranson, M., 'Targeting Urokinase and the Transferrin Receptor with Novel, Anti-Mitotic N-Alkylisatin Cytotoxin Conjugates Causes Selective Cancer Cell Death and Reduced Tumor Growth', Curr. Cancer Drug Targets, 2012, 12, 64-73.

Abbreviated CV

Qualifications

1964 BSc (1st Class Hons.) (University of Western Australia);

1968 PhD (Australian National University);

1975 Dip.Chem. Pharmacol. (Univeristy of Edinburgh);

1980 FRACI;

1991 FRSC.

Professional Experience

1967-1968 Harvard University Research Fellow in Chemistry;

1968-1991 University of Tasmania (Department of Chemistry);

1991-2007 University of Wollongong Professor of Organic Chemistry;

2001-2004 University of Wollongong Director, Institute for Biomolecular Science;

2008 - current  University of Wollongong Emeritus Professor;

2011 - RACI Distinguished Fellowship Award.