Stephen Ralph

Research Interests

Investigating Interactions between Metallointercalators and DNA

Nanofiltration using Carbon Nanotube Membranes

Separation and Recovery of Precious Metals using Conducting Polymers

Bioinorganic Chemistry of Metallodrugs

Molecular Cages for Metal Ions

Representative Publications

A.M.T. Bygott, R.J. Geue, S.F. Ralph, A.M. Sargeson and A.C. Willis, “Octahedral and Trigonal Prismatic Structure Preferences in a Bicyclic Hexaamine Cage for Zinc(II), Cadmium(II) and Mercury(II) Ions”, Dalton Transactions, 4778 (2007). – article featured on Journal cover – see below

S. Kemp, N.J. Wheate, S. Wang, J.G. Collins, S.F. Ralph, A.I. Day, V.J. Higgins and J.R. Aldrich-Wright, “Encapsulation of platinum(II)-based DNA intercalators Within Cucurbit[6,7,8]urils”, J. Biol. Inorg. Chem.,12, 969 (2007).

J. Talib, J.L. Beck and S.F. Ralph, “A Mass Spectrometric Investigation of the Binding of Gold Antiarthritic Agents and the Metabolite [Au(CN)₂]^- to Human Serum Albumin”, J. Biol. Inorg. Chem.,11, 559 (2006).

D.A. Reece, S.F. Ralph and G.G. Wallace, “Metal Transport Studies on Inherently Conducting Polymer Membranes Containing Cyclodextrin Dopants”, Journal of Membrane Science , 249, 9 (2005).

R. Gupta, J.L. Beck, M.M. Sheil and S.F. Ralph, “Identificationo of Bifunctional GA and AG Intrastrand Crosslinks Formed Between Cisplatin and DNA”, Journal of Inorganic Biochemistry , 99 , 552 (2005).

J. Ding, W.E. Price, S.F. Ralph and G.G. Wallace, “Electroless Recovery of Gold Chloride Using Inherently Conducting Polymers”, Polymer International, 53, 681 (2004).

T. Urathamakul, J.L. Beck, M.M. Sheil, J.R. Aldrich-Wright and S.F. Ralph, “A Mass Spectrometric Investigation of Non-Covalent Interactions Between Ruthenium Complexes and DNA”, Dalton Transactions, 2683 (2004).

Searchable Publication List

Current Students

PhD:

Jihan Talib Metallointercolators for transcription therapy

Shannon Little Electrocatalytic properties of nanostructured CNT materials

Suggested Topics for Future Students

Metal ion Chemistry of Me₈Tricosane, an Expanded Hexaamine Cage Ligand

Selective Filtration of Biomolecules using Carbon Nanotube Membranes

Novel Anticancer Approaches: Dinuclear Platinum Complexes that Bind Selectively to DNA Quadruplexes and Inhibit Telomerase

Abbreviated CV

B.Sc (Hons) University of Queensland
PhD University of Queensland
Postdoctoral fellow, University of Illinois
ARC Postdoctoral fellow, Australian National University

Last reviewed: 18 December, 2007