Stephen Ralph

Position: Associate Professor
Room: 18.226
Phone No: +61 2 4221 4286
E-mail: sralph@uow.edu.au
Lab: 18.109
Lab Phone: +61 2 4221 4394

Research Interests

• Investigating Interactions between Metallointercalators and DNA
• Nanofiltration using Carbon Nanotube Membranes
• Bioinorganic Chemistry of Metallodrugs
• Molecular Cages for Metal Ions                         

gold uptake by polypyrrole

silver on polypyrrole coated linen

Representative Publications

J. Boge, L.J. Sweetman, M. in het Panhuis and S.R. Ralph, “The Effect of Preparation Conditions and Biopolymer Dispersants on the Properties of SWNT Buckypapers”, J. Mat.Chem., DOI 10.1039/6914824h (2009) -article to be featured on back cover of Journal 
A.M.T. Bygott, R.J. Geue, S.F. Ralph, A.M. Sargeson and A.C. Willis, “Octahedral and Trigonal Prismatic Structure Preferences in a Bicyclic Hexaamine Cage for Zinc(II), Cadmium(II) and Mercury(II) Ions”, Dalton Transactions, 4778 (2007) – article featured on inside Journal front cover

J. Talib, J.L. Beck and S.F. Ralph, “A Mass Spectrometric Investigation of the Binding of Gold Antiarthritic Agents and the Metabolite [Au(CN)2]- to Human Serum Albumin”, J. Biol. Inorg. Chem.,11, 559 (2006).
D.A. Reece, S.F. Ralph and G.G. Wallace, “Metal Transport Studies on Inherently Conducting Polymer Membranes Containing Cyclodextrin Dopants”, Journal of Membrane Science , 249, 9 (2005).
J. Ding, W.E. Price, S.F. Ralph and G.G. Wallace, “Electroless Recovery of Gold Chloride Using Inherently Conducting Polymers”, Polymer International, 53, 681 (2004).
J. Talib, J.L. Beck, T. Urathamakul, C.D Nguyen, J.B. Aldrich-Wright, J.P. Mackay and S.F. Ralph, “A Mass Spectrometric Investigation of the Ability of Metal Complexes to Modulate Transcription Factor Activity”, Chemical Communications, 5546 (2009).
T. Urathamakul, D.J. Walker, J.L. Beck, T.B. Aldrich-Wright and S.F. Ralph, “Comparison of Mass Spectrometry and other Techniques for Probing Interactions Between Metal Complexes and DNA”, Inorg. Chem., 47, 6621 (2008).
J. Talib, C. Green, K.J. Davis, T. Urathamakul, J.L. Beck, J.R. Aldrich-Wright and S.F. Ralph, “A Comparison of the Binding of Metal Complexes to Duplex and Quadruplex DNA”, Dalton Transactions, 1018 (2008) – article featured on Journal front cover.

Searchable Publication List

Current Students

PhD:

Luke Sweetman  Nanofiltration using Carbon Nanotube Membranes
Shannon Little    Electrocatalytic properties of nanostructured CNT materials
Marceline Neg Alsieh  Environmental Applications of Conducting Polymers
Kimberley Davis  Probing the Biological Activity of Metallointercalators

Hons:

Lloyd James  Big Cages for Small Metal Ions

Suggested Topics for Future Students

Metal ion Chemistry of Me8Tricosane, an Expanded Hexaamine Cage Ligand
Selective Filtration of Biomolecules using Carbon Nanotube Membranes
Novel Anticancer Approaches: Metal Complexes that Bind Selectively to less Common DNA Secondary Structures
Biological Interactions and Cellular Localisation of Gold Antiarthritic Agents

Abbreviated CV

B.Sc (Hons) University of Queensland
PhD University of Queensland
Postdoctoral fellow, University of Illinois
ARC Postdoctoral fellow, Australian National University