Stephen Ralph   Position:   Associate Professor Room:   18.226 Phone No:   +61 2 4221 4286 Email:   stephen_ralph@uow.edu.au Lab:   18.213 Lab Phone:   +61 2 4221 3527

Research Interests

Towards Transcription Therapy using Metallointercalator

Separation and Recovery of Precious Metals using Conducting Polymers

Bioinorganic Chemistry of Metallodrugs

Molecular Cages for Metal Ions

 

Representative Publications

D.A. Reece, S.F. Ralph and G.G. Wallace, “Metal Transport Studies on Inherently Conducting Polymer Membranes Containing Cyclodextrin Dopants”, Journal of Membrane Science , 249, 9 (2005).

 R. Gupta, J.L. Beck, M.M. Sheil and S.F. Ralph, “Identificationo of Bifunctional GA and AG Intrastrand Crosslinks Formed Between Cisplatin and DNA”, Journal of Inorganic Biochemistry , 99 , 552 (2005).

J. Ding, W.E. Price, S.F. Ralph and G.G. Wallace, “Electroless Recovery of Gold Chloride Using Inherently Conducting Polymers”, Polymer International, 53, 681 (2004).

J.L. Beck, S. Ambehara, S.R. Yong, M.M. Sheil, J. de Jersey and S.F. Ralph, “Direct Observation of Covalent Adducts with Cys34 of Human Serum Albumin using Mass Spectrometry”, Analytical Biochemistry , 325 , 326 (2004).

T. Urathamakul, J.L. Beck, M.M. Sheil, J.R. Aldrich-Wright and S.F. Ralph, “A Mass Spectrometric Investigation of Non-Covalent Interactions Between Ruthenium Complexes and DNA”, Dalton Transactions , 2683 (2004).

V. Misoska, J. Ding, J.M. Davey, W.E. Price, S.F. Ralph and G.G. Wallace, “Polypyrrole Membranes Containing Chelating Ligands: Synthesis, Characterisation and Transport Studies”, Polymer, 42(21), 8571 (2001).

J.L. Beck, M.L. Colgrave, S.F. Ralph and M.M. Sheil, “Electrospray Ionization Mass Spectrometry of Oligonucleotide Complexes with Drugs, Metals and Proteins”, Mass Spectrometry Reviews , 20 , 61 (2001).

Searchable Publication List

 

Current Students

PhD:

Thitima Urathamakul

Mass spectrometry of ruthenium/DNA interactions

Jihan Talib

Metallointercolators for transcription therapy

 

Suggested Topics for Future Students

Interactions between gold anti-arthritic agents and proteins

Probing the DNA selectivity of platinum drugs using mass spectrometry

Synthesis of nanostructured conducting polymer membranes for separations applications

 

Abbreviated CV

B. Sc (Hons) University of Queensland
Ph. D University of Queensland
Postdoctoral fellow, University of Illinois
ARC Postdoctoral fellow, Australian National University