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Mark Wilson
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Professor |
| Position: |
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Director of
IBS |
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| Phone No: |
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+61 2 4221 4534 |
| Email: |
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mrw@uow.edu.au |
| Lab Phone: |
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+(61) 2 4221 4306 |
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Research Interests
Quality control mechanisms for extracellular protein
folding
Extracellular chaperones
Additional
Research Information
Representative Publications
Humphreys, D, Carver, J, Easterbrook-Smith, S B
and Wilson, M R (1999) Clusterin has chaperone-like
activity similar to that of small heat-shock proteins.
J. Biol. Chem. 274: 6875-6881
Poon, S, Easterbrook-Smith, S B, Rybchyn, M S, Carver,
J A and Wilson, M R (2000) Clusterin is an ATP-independent
chaperone with very broad specificity that stabilizes
stressed proteins in a folding-competent state. Biochemistry
39: 15953-15960
Poon, S, Rybchyn, M S, Easterbrook-Smith, S B, Carver,
J A, Pankhurst, G J and Wilson, M R (2002) Mildly
acidic pH activates the extracellular molecular chaperone
clusterin. J. Biol. Chem. 277: 39532-39540
Yerbury, J, Rybchyn, M, Easterbrook-Smith, S, Henriques,
C and Wilson, M R (2005) The acute phase protein
haptoglobin is a mammalian extracellular chaperone
with an action similar to clusterin. Biochemistry
44: 10914-10925
Yerbury, J, Stewart, E, Wyatt, A and Wilson,
M R (2005) Quality control of protein folding in extracellular
space. EMBO Reports 6: 1131-1136
Searchable Publication List
Current Students
PhD
Katie French
Chaperone activity of alpha-2-macroglobulin
Elise Stewart
Structural and Functional Studies of Clusterin
Amy Wyatt
Disposal of misfolded extracellular proteins
Justin Yerbury
Extracellular chaperones and amyloid
Suggested Topics for Future Students
(i) Development of recombinant sources of extracellular
chaperones for potential therapeutic applications.
(ii) Investigating the involvement of extracellular
chaperones in inflammatory disease.
Abbreviated CV
Employment History
Professor, University of Wollongong, 2004 -
Associate Professor, University of Wollongong, 2000-
2004
Senior Lecturer, University of Wollongong 1996- 1999
Lecturer, University of Wollongong 1994-1995
The Medical Foundation Medical Research Fellow 1993
NH&MRC Research Officer / Snr Research Officer,
Dept. of Biochemistry, Univ. of Sydney, 1990-1992
Research Fellow, Department of Biochemistry, Univ.of
Sydney, 1988-90
Research Scientist, Monoclonal Australia Ltd., 65
Dickson Ave., Artarmon, 2064, 1986-88
NH&MRC Research Officer, Clinical Immunology,
Univ. of Sydney, 1986
NH&MRC Research Assistant, Clinical Immunology,
Univ. of Sydney, 1985
Academic Degrees
PhD The University of Sydney 1985
BSc (Hons) (First class) The University of Sydney
1980
Prizes, Scholarships, Fellowships and Awards
Outstanding Achievement in Teaching Award, Australian
College of Education 1997
VC's Excellence in Teaching Award, University ofWollongong
1997
Travelling Fellowship The Faculty of Medicine, University
of Sydney 1993
Medical Research Fellowship, The Medical Foundation
1993
Commonwealth Postgraduate Scholarship 1981-85
G.S.Caird Scholarship, Biology IIIE, The University
of Sydney 1979
Haswell Prize, Biology IIIE, The University of Sydney
1978
G.S.Caird Scholarship, Biology IIE, The University
of Sydney 1977
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