Olsson Lab
Immunobiology and Oxidative Stress
Do males with hormonal profiles associated with stress suffer
from higher plasma levels of oxidants (e.g. lipid peroxidation),
as
would be predicted from higher levels of basal metabolism?
Do they show premature ageing as revealed by telomere shortening?
Antioxidants (e.g. vitamin C and E) are well known for their
beneficial effects for preventing degenerative diseases such
as cancer.
In wild populations carotenoids are the most common
antioxidant. In painted dragons, carotenoids are important
components
in the development of male colouration and males of the three
colour morphs (red, orange and yellow) may differ in
how they ingest or metabolize carotenoids.
We would like to understand the
underlying mechanism as to if and why these colours evolve
into honest signals,
assuming the colours reliably indicate some quality of the
signaler.
To do this we need to be able to dissect the independent and
relative actions of immunogenotype, oxidant and carotenoids
in a causal chain between ctyochemistry and an individual’s
relative fitness. In this way we hope to tease out the mechanistic
underpinnings of male colouration and its link to fitness.
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