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Research Interests

Protein misfolding, aggregation and neurodegenerative disease

Protein aggregation and neuro-inflammation.

Extracellular chaperones and protein homeostasis.

Representative Publications

Yerbury JJ, Stewart EM, Wyatt AR, Wilson MR. (2005) Quality control of protein folding in extracellular space. EMBO Reports 6: 1131-1136

Yerbury, JJ, Poon, S, Meehan, S, Thompson, B, Kumita, JR, Dobson, CM and Wilson, MR. (2007) The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with pre-fibrillar structures. FASEB Journal 21: 2312-22 (IF 6.791, ranked 31/263)

Wilson MR, Yerbury JJ, Poon S. (2008) The role of extracellular chaperones in amyloid formation. Molecular BioSystems. 4, 42-52.

Yerbury JJ and Wilson MR. (2009) Extracellular chaperones modulate the effects of Alzheimer’s patient CSF on Aβ toxicity and uptake. Cell Stress and Chaperones. May 27. [Epub ahead of print]

Future Topics for Students

Examining the relationship between the aggregation propensity and the ability to activate glial cells in Motor Neurone Disease causing SOD1 mutations.

Investigating the affect of extracellular Motor Neurone Disease associated mutant SOD1 on astrocyte function and phenotype.

Abbreviated CV

Employment History

Bill Gole Motor Neurone Disease Postdoctoral Fellow, University of Wollongong, 2009 -

ARC International Linkage Fellow, University of Cambridge, UK 2008-2009

Lecturer/Research Fellow, University of Wollongong, 2008

Research Assistant, University of Wollongong, 2002-2003

Academic Degrees

PhD, University of Wollongong, 2008

BSc (Hons) (First class) University of Wollongong, 2004

Prizes, Fellowships and Awards

Bill Gole Postdoctoral MND Research Fellowship, 2009

Australian Research Council International Linkage Fellowship, 2008

The Australian Society for Medical Research Young Investigator Award, 2004