Preclinical Development of Novel Antibacterial Peptoids
Targeting Antibiotic Resistant Bacteria
Summary:
The emergence of bacterial strains resistant to antibiotics
has created a major healthcare problem in the treatment of some bacterial
infections. We have developed new drugs with activity against a range
of bacteria including resistant ones. It is now important to complete
full pre-clinical evaluations of our compounds including demonstrating
activity in vivo. This proposal will complete the development of
the compounds in readiness for assessment as potential therapeutics
in the clinic.
