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Dr Chao Deng

BSc, MSc, PhD

Position:

• Senior Research Fellow

Teaching and coordinating:

• Honours and postgraduate research student supervision

Research Interests:

• Pathological alterations of the muscarinic, glutamate, serotonin and GABA receptors in the superior temporal gyrus in schizophrenia
• Development of an animal model of schizophrenia (Phencyclidine model).
• Neuropharmacological mechanisms of antipsychotic drugs, particularly on regulating brain gene and protein expression and antipsychotic-induced obesity
• Neuroendocrinological regulation of feeding and body weight (obesity)
• Effects of early experience and hormones on the development of brain lateralization

Publications:

Searchable RIS publications from 2000 to date

• Weston-Green K, Huang X-F, Han M, Deng C. (2008) The effects of antipsychotics on the density of cannabinoid receptors in the dorsal vagal complex of rats: Implications for olanzapine-induced weight gain. International Journal of Neuropsychopharmacology p.1-9; doi:10.1017/S1461145708008560
  
  
• Han M., Deng C, Burne THJ, Newell K, and Huang X-F. (2008) Short- and long-term effects of antipsychotic drug treatment on weight gain and H1 receptor expression. Psychoneuroendocrinology 33:569-580
  
  
• du Bois T, Huang XF, Deng C. (2008) Perinatal administration of PCP alters adult behaviour in female Sprague-Dawley rats. Behavioural Brain Research 188:416-419
  
  
• Rahardjo GL, Huang XF, Tan YY, and Deng C. (2007) Decreased plasma PYY accompanied by an elevated PYY and Y2 receptor binding sites in the medulla oblongata of diet-induced obese mice. Endocrinology 148: 4704-4710
  
  
• Deng, C and Huang, X-F. (2005) Decreased density of muscarinic receptors in the superior temporal gyrus in schizophrenia.  Journal of Neuroscience Research 81:883-890
  
  
• Deng, C. (2005) Interactions between genetic and environmental factors determine direction of population lateralization. Behavioral and Brain Sciences 28 (4):598-598